Identification | Back Directory | [Name]
(-)-3,4-Dihydroxynorephedrine | [CAS]
829-74-3 | [Synonyms]
BA 2818 Nordefri l-Cobefrin CORBADRINE Neo-cobefrin Isoadrenaline LEVONORDEFRIN D-(-)-Cobefrin Levonordefrin Base Dioxynorepinephrine Levonordefrin (200 mg) L-α-Methylnoradrenaline Corbadrine, Levonordefrin, (-)-α-methylnorepinephrine (-)3,4-DIHYDROXYNOREPHEDRINE Dihydroxyphenylpropanolamine (-)-3,4-Dihydroxynorephedrine (-)-3,4-DIHYDROXYNOREPHREDRINE 3,4-Dihydrophenyl-1-amino-2-propanol-1 4-(2-amino-1-hydroxy-propyl)pyrocatechol Corbadrine, Levonordefrin, l-Norephedrine (-)-3,4-DIHYDROXYNOREPHEDRINE, TECH., 90 % (-)-3,4-DIHYDROXYNOREPHEDRINE*APPROX. 90 % 4-(2-Amino-1-hydroxypropyl)benzene-1,2-diol 4-[2-AMINO-1-HYDROXYPROPYL]-1,2-BENZENEDIOL 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)- (1R,2S)-2-Amino-1-(3,4-dihydroxyphenyl)-1-propanol 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)- (9CI) BENZYL ALCOHOL, alpha-(1-AMINOETHYL)-3,4-DIHYDROXY- (-)-4-[(1R,2S)-2-Amino-1-hydroxypropyl]-1,2-benzenediol α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, (-)-α-Methylnorepinephrine, 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, L-4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, (-)-α-Methylnorepinephrine, 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, L-4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, Levonordefrin | [Molecular Formula]
C9H13NO3 | [MDL Number]
MFCD00134415 | [MOL File]
829-74-3.mol | [Molecular Weight]
183.2 |
Chemical Properties | Back Directory | [Appearance]
White Powder | [Melting point ]
212-215°C dec. | [alpha ]
D25 -31.0° (c = 0.5 in 0.01N HCl) | [Boiling point ]
431.6±40.0 °C(Predicted) | [density ]
1.328±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO: soluble5mg/mL, clear (warmed) | [form ]
powder | [pka]
9.59±0.10(Predicted) | [color ]
white to light brown | [Merck ]
13,6725 |
Hazard Information | Back Directory | [Chemical Properties]
White Powder | [Uses]
A vasoconstrictor which also increases the potency and duration of anesthesia produced by local anesthetics | [Uses]
Vasoconstrictor;Adrenergic receptor agonist | [Definition]
ChEBI: Alpha-methylnoradrenaline is a catecholamine in which the 2-aminoethyl group is substituted with a hydroxy group at C-1 and a methyl group at C-2, with configurations 1R,2S. A metabolite of alpha-methyl-L-dopa, it is an alpha2-adrenergic agonist and acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. It has a role as an alpha-adrenergic agonist, a vasoconstrictor agent and a nasal decongestant. | [Brand name]
Neo-Cobefrin (Cook-Waite). |
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