ChemicalBook--->CAS DataBase List--->829-74-3

829-74-3

829-74-3 Structure

829-74-3 Structure
IdentificationBack Directory
[Name]

(-)-3,4-Dihydroxynorephedrine
[CAS]

829-74-3
[Synonyms]

BA 2818
Nordefri
l-Cobefrin
CORBADRINE
Neo-cobefrin
Isoadrenaline
LEVONORDEFRIN
D-(-)-Cobefrin
Levonordefrin Base
Dioxynorepinephrine
Levonordefrin (200 mg)
L-α-Methylnoradrenaline
Corbadrine, Levonordefrin,
(-)-α-methylnorepinephrine
(-)3,4-DIHYDROXYNOREPHEDRINE
Dihydroxyphenylpropanolamine
(-)-3,4-Dihydroxynorephedrine
(-)-3,4-DIHYDROXYNOREPHREDRINE
3,4-Dihydrophenyl-1-amino-2-propanol-1
4-(2-amino-1-hydroxy-propyl)pyrocatechol
Corbadrine, Levonordefrin, l-Norephedrine
(-)-3,4-DIHYDROXYNOREPHEDRINE, TECH., 90 %
(-)-3,4-DIHYDROXYNOREPHEDRINE*APPROX. 90 %
4-(2-Amino-1-hydroxypropyl)benzene-1,2-diol
4-[2-AMINO-1-HYDROXYPROPYL]-1,2-BENZENEDIOL
1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-
(1R,2S)-2-Amino-1-(3,4-dihydroxyphenyl)-1-propanol
1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)- (9CI)
BENZYL ALCOHOL, alpha-(1-AMINOETHYL)-3,4-DIHYDROXY-
(-)-4-[(1R,2S)-2-Amino-1-hydroxypropyl]-1,2-benzenediol
α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, (-)-α-Methylnorepinephrine, 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, L-4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol
α-(1-Aminoethyl)-3,4-dihydroxybenzyl alcohol, (-)-α-Methylnorepinephrine, 4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, L-4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, Levonordefrin
[Molecular Formula]

C9H13NO3
[MDL Number]

MFCD00134415
[MOL File]

829-74-3.mol
[Molecular Weight]

183.2
Chemical PropertiesBack Directory
[Appearance]

White Powder
[Melting point ]

212-215°C dec.
[alpha ]

D25 -31.0° (c = 0.5 in 0.01N HCl)
[Boiling point ]

431.6±40.0 °C(Predicted)
[density ]

1.328±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

DMSO: soluble5mg/mL, clear (warmed)
[form ]

powder
[pka]

9.59±0.10(Predicted)
[color ]

white to light brown
[Merck ]

13,6725
Hazard InformationBack Directory
[Chemical Properties]

White Powder
[Uses]

A vasoconstrictor which also increases the potency and duration of anesthesia produced by local anesthetics
[Uses]

Vasoconstrictor;Adrenergic receptor agonist
[Definition]

ChEBI: Alpha-methylnoradrenaline is a catecholamine in which the 2-aminoethyl group is substituted with a hydroxy group at C-1 and a methyl group at C-2, with configurations 1R,2S. A metabolite of alpha-methyl-L-dopa, it is an alpha2-adrenergic agonist and acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. It has a role as an alpha-adrenergic agonist, a vasoconstrictor agent and a nasal decongestant.
[Brand name]

Neo-Cobefrin (Cook-Waite).
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22-36/37/38
[Safety Statements ]

26-36
[RIDADR ]

UN 2811 6.1 / PGII
[WGK Germany ]

3
[HS Code ]

2922504500
[Toxicity]

LD50 in mice (mg/kg): 12.6 i.v. (Luduena)
Tags:829-74-3 Related Product Information
150-13-0 616-30-8 100-41-4 62-53-3 53-06-5 50-50-0 121-57-3 99-96-7 56-40-6 4111-54-0 300-57-2 71-43-2 118-92-3 50-98-6 3198-15-0 299-42-3 118-08-1 485-49-4