ChemicalBook--->CAS DataBase List--->840506-29-8

840506-29-8

840506-29-8 Structure

840506-29-8 Structure
IdentificationBack Directory
[Name]

Acelarin
[CAS]

840506-29-8
[Synonyms]

Acelarin
NUC-1031
NUC-1031 impurity
Acelarin(NUC1031)
NUC-1031; NUC1031; NUC 1031
N-(2'-Deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl)-L-alanine phenylmethyl ester
N-(2'-Deoxy-2',2'-difluorocytidine 5'-P-phenyl phosphate) L-alanine benzyl ester
L-Alanine, N-(2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl)-, phenylmethyl ester
[Molecular Formula]

C25H27F2N4O8P
[MDL Number]

MFCD27987942
[MOL File]

840506-29-8.mol
[Molecular Weight]

580.47
Chemical PropertiesBack Directory
[Boiling point ]

708.4±70.0 °C(Predicted)
[density ]

1.51±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 12 mg/mL; DMSO: 14 mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL; Ethanol: 10 mg/mL
[form ]

A crystalline solid
[pka]

11.46±0.70(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Acelarin is a phosphoramidate transformation of the pancreatic and ovarian cancer chemotherapy Gemcitabine; and the first anti-cancer ProTide to enter the clinic.
[storage]

Store at -20°C
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