| Identification | Back Directory | [Name]
Aflibercept | [CAS]
845771-78-0 | [Synonyms]
Eylea
AFLIBERCEPT
9: PN: US20050043236SEQID: 10 unclaiMed protein (9CI) |
| Hazard Information | Back Directory | [Clinical Use]
Antineoplastic agent:
Treatment of metastatic colorectal cancer | [Drug interactions]
Potentially hazardous interactions with other drugs
None known | [Metabolism]
No metabolism studies have been conducted with
aflibercept since it is a protein. Aflibercept is expected to
degrade to small peptides and individual amino acids.
Free aflibercept is mainly cleared by binding to
endogenous VEGF to form a stable, inactive complex. As
with other large proteins, both free and bound aflibercept,
are expected to be cleared, more slowly, by other biological
mechanisms, such as proteolytic catabolism. |
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