| Identification | Back Directory | [Name]
EURYCOMANONE | [CAS]
84633-29-4 | [Synonyms]
NSC 339187
EURYCOMANONE
pasakbumin-a
Eurycoma longifolia
Eurycomanone (~90%)
EurycomalongifoliaJack
Extract of Orion nigrum
Eurycomanone (Pasakbumin A)
Extract of amaryllis asiatica l
Eurycomanone (Synonyms: Pasakbumin A)
11-beta,12-alpha,15-beta)-betdihydrate
Eurycomanone, 98%, from Eurycoma longifolia
11,2o-epoxy-1,11,12,14,15-pentahydroxy-13(21)-diene-(1-picrasa-16-dione
11β,20-Epoxy-1β,11,12α,14,15β-pentahydroxypicrasa-3,13(21)-diene-2,16-dione
Picrasa-3,13(21)-diene-2,16-dione,11,20-epoxy-1,11,12,14,15-pentahydroxy-, (1b,11b,12a,15b)-
Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,11β,12α,15β)-
(1beta,8xi,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-11,20-epoxypicrasa-3,13(21)-diene-2,16-dione | [Molecular Formula]
C20H28O11 | [MDL Number]
MFCD01704311 | [MOL File]
84633-29-4.mol | [Molecular Weight]
444.43 |
| Chemical Properties | Back Directory | [Melting point ]
273-285℃ (methanol ethyl ether ) | [Boiling point ]
669.5±55.0 °C(Predicted) | [density ]
1.63±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
11.29±0.70(Predicted) | [color ]
Off-White to Pale Beige |
| Hazard Information | Back Directory | [Uses]
Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.
| [Definition]
ChEBI: A quassinoid isolated from Eurycoma longifolia and has been shown to exhibit antineoplastic and antimalarial activties. | [storage]
Store at -20°C |
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