| Identification | Back Directory | [Name]
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate | [CAS]
85267-60-3 | [Synonyms]
3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine
Uridine, 2'-deoxy-5-[2-(trimethylsilyl)ethynyl]-, 3',5'-diacetate | [Molecular Formula]
C18H24N2O7Si | [MOL File]
85267-60-3.mol | [Molecular Weight]
408.48 |
| Hazard Information | Back Directory | [Uses]
3',5'-di-O-acetyl-2'-deoxy-5-((trimethylsilyl)ethynyl)uridine can be used as organic intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
1.Add DMAP (0.16 mmol, 20 mg) to a stirred suspension of 2'-deoxyuridine (1 mmol, 228 mg) in acetic anhydride (7.5 mL).2.Observe the reaction mixture become homogenous for 6 hours.3.Remove the volatiles in vacuum.4.Purify the residue by flash chromatography on silica gel eluted with EA/cyclohexane (4:1 → 19:1, v/v) to obtain 3',5'-di-O-acetyl-2'-deoxyuridine. |
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