Identification | Back Directory | [Name]
Isoleucinamide, (βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-, cyclic (15→3)-ether, (2E)- | [CAS]
89085-54-1 | [Synonyms]
Phomopsinamine Isoleucinamide, (βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-, cyclic (15→3)-ether, (2E)- | [Molecular Formula]
C32H43ClN6O8 | [MOL File]
89085-54-1.mol | [Molecular Weight]
675.18 |
Hazard Information | Back Directory | [Biological Activity]
Phomopsinamine is an inhibitor of microtubule polymerization and a derivative of phomopsin A .1 It inhibits the rate and extent of polymerization of tubulin isolated from ovine brain (IC50s = 0.53 and 0.59 μM, respectively). | [References]
1.Lacey, E., Edgar, J.A., and Culvenor, C.C.Interaction of phomopsin A and related compounds with purified sheep brain tubulinBiochem. Pharmacol.36(13)2133-2138(1987)
|
|
Company Name: |
BOC Sciences
|
Tel: |
1-631-485-4226; 16314854226 |
Website: |
https://www.bocsci.com |
Company Name: |
ChemeGen 中国
|
Tel: |
18818260767 |
Website: |
https://www.chemegen.com |
|