113558-15-9
113558-15-9 结构式
基本信息
宝藿苷I
宝藿苷Ⅰ
脱水淫羊藿苷)
宝藿苷I对照品,
宝藿苷I(标准品)
宝藿苷I,淫羊藿次苷Ⅱ
宝藿苷Ⅰ(分析标准品)
宝藿苷I, 来源于淫羊藿
宝藿苷I/ 淫羊藿次苷2
Icariin II
Icarisid II
Baohuside I
BaohuosideⅠ
Baohuoside-1
baohuoside I
Icariside II 113558-15-9
Baohuoside I(Icariside II)
Baohuoside I Baohuside I
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-N0011 | 宝藿苷I Baohuoside I | 113558-15-9 | 5 mg | 800元 |
| 2024/04/30 | S3840 | 宝藿苷I Baohuoside I | 113558-15-9 | 5mg | 876.5元 |
| 2024/04/30 | HY-N0011 | 宝藿苷I Baohuoside I | 113558-15-9 | 10mg | 1200元 |
常见问题列表
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CXCR4
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Baohuoside I is an inhibitor of CXCR4, and downregulates CXCR4 expression at 12-25 μM. Baohuoside I (0-25 μM) suppresses NF-κB activation in a dose-dependent manner, suppresses CXCL12 induced the invasion of cervical cancer cells. Baohuoside I also inhibits invasion of breast cancer cells. Baohuoside I inhibits A549 cell viability, with IC 50 s of 25.1 μM at 24 h, 11.5 μM and 9.6 μM at 48 h and 72 h, respectively. Baohuoside I ((25 μM) suppresses the caspase cascade in A549 cells, elevates ROS levels and activates JNK and p38 MAPK signaling cascade. Baohuoside I (3.125, 6.25, 12.5, 25.0 and 50.0 µg/mL) significantly and dose-dependently blocks the growth of esophageal squamous cell carcinoma Eca109 cells, with an IC 50 of 4.8 µg/mL at 48 h.
Baohuoside I (25 mg/kg) decreases β-catenin protein levels, cyclin D1 and survivin expression in nude mice.