125720-21-0
中文名称
FIBRONECTIN ADHESION-PROMOTING PEPTIDE
CAS
125720-21-0
分子式
C47H74N16O10
分子量
1023.19
MOL 文件
125720-21-0.mol
更新日期
2024/06/03 09:46:34
125720-21-0 结构式
基本信息
英文别名
WQPPRARIHEPARIN-BINDING PEPTIDE
TRP-GLN-PRO-PRO-ARG-ALA-ARG-ILE
H-TRP-GLN-PRO-PRO-ARG-ALA-ARG-ILE-OH
FIBRONECTIN ADHESION-PROMOTING PEPTIDE
Fibronectin Adhesion-promoting Peptide >=95% (HPLC)
Fibronectin Adhesion-Promoting Peptide / Heparin-Binding Peptide
L-Isoleucine, L-tryptophyl-L-glutaminyl-L-prolyl-L-prolyl-L-arginyl-L-alanyl-L-arginyl-
常见问题列表
生物活性
Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) 是一种肝素结合氨基酸序列，这段序列存在于纤连蛋白 C-端的肝素结合域中。Fibronectin Adhesion-promoting Peptide 促进间充质干细胞 (MSC) 球状体组装成更大的聚集体。Fibronectin Adhesion-promoting Peptide 通过与细胞的肝素结合区反应直接促进内皮细胞的粘附、扩散和迁移。体外研究
GRGDS and Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide: WQPPRARI) micropatterns increase the endothelialisation of prosthetic materials in vitro. Fibronectin Adhesion-promoting Peptide also enhances haptotactic cell migration. The anti-apoptotic effects of fibronectin require the presence of the WQPPRARI sequence, which may be due to synergistic survival signals mediated by this sequence and by the RGD motif.
RDGS and Fibronectin Adhesion-promoting Peptide promote cell adhesion through different activation pathways that induce different forms of adhesion which can be highlighted through the analysis of focal and fibrillar contacts.