16611-84-0
16611-84-0 结构式
基本信息
氢化腰果酸
氢化漆树酸
漆树酸/氢化白果酸
银杏酸C15:0&NBSP
2-羟基-6-十五基苯甲酸
NSC 333857
NSC 229596
Anachardic acid
22:0-Anacardic acid
Anacardic Acid 15:0
(15:0)-Anacardic acid
Cyclogallipharic acid
PENTADECYLSALICYLICACID
Hodrogenated anacardic acid
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | S7582 | Anacardic Acid | 16611-84-0 | 10mM (1mL in DMSO) | 810.81元 |
| 2024/04/30 | S7582 | 漆树酸 Anacardic Acid | 16611-84-0 | 50mg | 2765.05元 |
| 2024/01/16 | S7582 | 漆树酸 Anacardic Acid | 16611-84-0 | 10mg | 804.57元 |
常见问题列表
| Target | Value |
|
Tip60
(Cell-free assay) | |
|
PCAF
(Cell-free assay) | 5 μM |
|
p300/CBP
(Cell-free assay) | 8.5 μM |
Anacardic Acid is a histone acetyltransferase, inhibits HAT activity of p300 and PCAF, with IC 50 s of ∼8.5 μM and ∼5 μM, respectively. Anacardic Acid (300 μM) inhibits mycelial growth. Anacardic Acid (50 μM) induces apoptosis-like characteristics in M. oryzae , and the effect is caspase independent. Anacardic Acid (1-80 μM) leads to loss of mitochondrial potential. Anacardic Acid (1-60 μM) also exhibits antioxidant activity in M. oryzae .
Anacardic acid (5 mg/kg, i.p.) attenuates the binding of HATs to the promoter of MEF2A and reverse hyperacetylation of H3K9ac caused by phenylephrine in C57BL/6 mice. Anacardic acid inhibits the level of transcription on MEF2A and cardiac development-related downstream genes, attenuates the protein overexpression of cardiac downstream genes caused by phenylephrine, reverses and attenuates cardiac hypertrophy in the hearts of mice exposed to phenylephrine, and attenuates the left ventricular pressure and improves cardiac function in the cardiac hypertrophy mice.