21516-68-7
中文名称
红曲
英文名称
MONASCIN
CAS
21516-68-7
分子式
C21H26O5
分子量
358.43
MOL 文件
21516-68-7.mol
更新日期
2024/05/20 10:34:41
21516-68-7 结构式
基本信息
中文别名
红曲素功能性红曲
红曲素/红曲霉素
英文别名
MONASCINCcris 9138
Monascoflavin
Monascin >=97.0% (HPLC)
(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione
(3S)-3aα,4,8,9a-Tetrahydro-9aβ-methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
(3S,3aR,9aR)-3a,4,8,9a-Tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-
物理化学性质
熔点145 °C
沸点574.6±50.0 °C(Predicted)
密度1.18±0.1 g/cm3(Predicted)
储存条件2-8°C
酸度系数(pKa)10.59±0.60(Predicted)
BRN51355
InChIKeyXXKNHBAFFJINCK-RVEJDSBJSA-N
常见问题列表
生物活性
Monascin 是可从红曲米中提取得到的一种氮杂类色素，有口服活性，具有抗肿瘤和抗炎活性。Monascin 还能抑制NOR 的激活。体内研究
Monascin (0.0025% in drinking water; mice) appears effective for the inhibition of UVB-initiated carcinogenesis on mouse skin.
| Animal Model: | SENCAR mouse using a UVB irradiation as an initiator and TPA as a promoter. |
| Dosage: | 0.0025% in drinking water. |
| Administration: | Orally daily for 2 weeks in drinking water. |
| Result: | Reduced the number of the papillomas. |