30045-16-0
30045-16-0 结构式
基本信息
脱氢延胡索碱
去氢延胡索素
去氢延胡索甲素
脱氢紫堇碱(标准品)
去氢紫堇碱(标准品)
脱氢紫堇碱(去氢紫堇碱
去氢紫堇碱、去氢延胡索甲素
脱氢紫堇碱,去氢紫堇碱、去氢延胡索甲素
去氢紫堇碱,去氢延胡索甲素,去氢延胡索素
dehydeocorydaline
13-Methylpalmatine
DEHYDROCORYDALINE98%
5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium
13-Methyl-2,3,9,10-tetramethoxy-5,6-dihydrodibenzo[a,g]quinolizinium
Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-
物理化学性质
常见问题列表
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Bcl-2
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Bax
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Caspase-7
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Caspase-8
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PARP
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Dehydrocorydaline (0-200 μM) treatment significantly inhibits the growth of MCF-7 cells in a dose-dependent manner. The cell viability is decreased by approximate 40% after 24 h of 200 μM Dehydrocorydaline.
Dehydrocorydaline (0-200 μM)dose-dependently increases Bax protein expression and decreases Bcl-2 protein expression.
Dehydrocorydaline (0-200 μM)induces activation of caspase-7,-8 and the cleavage of PARP without affecting caspase-9.
Dehydrocorydaline manifests a low acute toxicity with an LD 50 of about 277.5±19.0 mg/kg body weight in mice following oral administration and 21.1±1.4 mg/kg for intraperitoneal injection.