38562-01-5
中文名称
地诺前列素氨丁三醇
英文名称
Dinoprost tromethamine
CAS
38562-01-5
分子式
C24H45NO8
分子量
475.62
MOL 文件
38562-01-5.mol
更新日期
2024/05/22 21:33:10
38562-01-5 结构式
基本信息
中文别名
缓血酸胺盐二诺前列特罗莫
地诺前列素氮三丁醇
氨丁三醇地诺前列素
地诺前列素氨丁三醇
地诺前列腺素 氨丁三醇
前列腺素 F2ΑTRIS 盐
地诺前列素氨丁三醇 EP标准品
地诺前列素氨丁三醇 USP标准品
地诺前列素氨丁三醇/前列腺素F2ΑTRIS盐
英文别名
583eu14585
lutalyse
PGF2αTris
Ensaprost
u-14,583e
PGF2ALPHA
Zinoprost
PGF2a-THAM
THAM PGF2α
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
熔点100-101°
储存条件−20°C
储存条件-20°C
溶解度H2O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.
溶解度在水中的溶解度1 mg/mL水溶液在2-8°C下可稳定保存30天，在−0°C下单独保存数月使用等分试样。避免反复冷冻/解冻循环。
形态powder
颜色white
Merck13,7970
BRN4087514
稳定性吸湿性
InChIKeyIYGXEHDCSOYNKY-RZHHZEQLSA-N
安全数据
警示词危险
危险性描述H302-H360FD
危险品标志T
危险类别码60-22
安全说明53-45
WGK Germany3
WGK Germany3
RTECS号UK8025000
F8-10
海关编码2937500000
地诺前列素氨丁三醇价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-12956A | 地诺前列素氨丁三醇 Dinoprost tromethamine salt | 38562-01-5 | 5mg | 550元 |
| 2024/04/30 | HY-12956A | 地诺前列素氨丁三醇 Dinoprost tromethamine salt | 38562-01-5 | 10mM * 1mLin DMSO | 605元 |
| 2024/04/30 | HY-12956A | 地诺前列素氨丁三醇 Dinoprost tromethamine salt | 38562-01-5 | 10mg | 780元 |
常见问题列表
生物活性
Dinoprost Tromethamine (Dinolytic, PGF2-alpha tham, Zinoprost, Prostin F2 alpha, Dinoprost Trometamol) 是一种合成的prostaglandin F2 alpha类似物，prostaglandin F2 alpha可通过直接作用于黄体素，刺激子宫肌层活性、使宫颈舒张、抑制黄体类固醇生成、诱导黄体溶解。靶点
|
FP Receptor
|
Human Endogenous Metabolite
|
体外研究
Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt; 1 μM; for 24 hours) induces ER stress, autophagy, and apoptosis in goat luteal cells.
Dinoprost tromethamine salt (1 μM; for 24 hours) significantly increases the expression of GRP78 and UPR sensors.
Apoptosis Analysis
| Cell Line: | Goat luteal cells |
| Concentration: | 1 μM |
| Incubation Time: | For 24 hours |
| Result: | Significantly increased the apoptotic rate (15.62±3.12%). |
Cell Autophagy Assay
| Cell Line: | Goat luteal cells |
| Concentration: | 1 μM |
| Incubation Time: | For 24 hours |
| Result: | There was extensive overlap between LC3 and LAMP1 in luteal cells and autophagolysosomes were formed in goat luteal cells. |
Western Blot Analysis
| Cell Line: | Goat luteal cells |
| Concentration: | 1 μM |
| Incubation Time: | For 24 hours |
| Result: | The expression of GRP78 and UPR sensors including cleaved ATF6, phosphorylated-EIF2S1, EIF2S1, ATF4, phosphorylated-IRE1, autophagy-related protein LC3-II, and pro-apoptosis factor cleaved Caspase3 increased significantly in the cells. |