477600-73-0
中文名称
N-甲基-N-((3R,4R)-4-甲基-1-苄基-3-哌啶基)-7H-吡咯并[2,3-D]嘧啶-4-胺
英文名称
7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-
CAS
477600-73-0
分子式
C20H25N5
分子量
335.45
MOL 文件
477600-73-0.mol
更新日期
2024/05/25 17:42:24
477600-73-0 结构式
基本信息
中文别名
依法替尼中间体托伐替尼杂质D
托法杂质M-RR
托法替尼杂质 1
托法替布杂质TZ4
N-((3R,4R)-1-苄基-4-甲基哌啶-3-基)-N-甲基-7H-吡咯[2,3-D]嘧啶-4-胺
N-[(3R,4R)-1-苄基-4-甲基-3-哌啶基]-N-甲基-7H-吡咯并[2,3-D]嘧啶-4-胺
N-((3R,4R)-1-苄基-4-甲基哌啶-3-基)-N-甲基-7H-吡咯并[2,3-D]嘧啶-4-胺
N-甲基-N-((3R,4R)-4-甲基-1-苄基-3-哌啶基)-7H-吡咯并[2,3-D]嘧啶-4-胺
(3R,4R)-(1-苄基-4-甲基-哌啶-3-基)-甲基-(7H-吡咯并[2,3-D]嘧啶-4-基)-胺
英文别名
N-((3R,4R)Tofacitinib-10
Tofacitib impurity TZ4
Tasocitinib Intermediate
-1-Benzyl-4-methylpiperidin-3-yl)
N-((3R,4R)-1-BENZYL-4-METHYLPIPERIDIN-3-YL)-N-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-
N-[(3R,4R)-1-benzyl-4-methyl-3-piperidyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
(3R, 4R)-(1-benzyl-4-methyl-piperidin-3-yl) -methyl- (7H-pyrrolo [2,3-d] pyrimidin-4-yl) -amine
N-Methyl-N-[(3R,4R)-4-methyl-1-(phenylmethyl)-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
1H-Pyrrolo[2,3-d]pyriMidin-4-aMine,N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-
所属类别
医药中间体：原料药中间体物理化学性质
熔点67-69℃
密度1.205±0.06 g/cm3(Predicted)
储存条件Keep in dark place,Inert atmosphere,2-8°C
酸度系数(pKa)13.36±0.50(Predicted)