487-79-6
中文名称
红藻氨酸, **
英文名称
KAINIC ACID
CAS
487-79-6
分子式
C10H15NO4
分子量
213.23
MOL 文件
487-79-6.mol
更新日期
2024/05/21 12:59:08
487-79-6 结构式
基本信息
中文别名
卡英酸鷓鴣菜酸
紅藻胺酸
海人草酸
红藻氨酸, **
ALPHA-红藻氨酸
(2S,3S,4S)-3-(羧基甲基)-4-(丙-1-烯-2-基)吡咯烷-2-羧酸
英文别名
KAINATE(-)-α-Kainic Acid
Kainic
C12819
digenin
helminal
(3a&alpha
Kainicaci
,4-beta))-
KAINIC ACID
所属类别
有机原料：羧酸类化合物及衍生物物理化学性质
熔点253-254 C
比旋光度D24 -14.8° (c = 1.01)
沸点353.22°C (rough estimate)
密度1.2177 (rough estimate)
折射率1.4368 (estimate)
储存条件2-8°C
储存条件Keep in dark place,Sealed in dry,2-8°C
溶解度H2O: soluble
溶解度可溶于水中
酸度系数(pKa)2.03±0.60(Predicted)
形态白色至类白色固体
颜色白色
水溶解性Soluble to 25 mM in water
稳定性自购买之日起 1 年内保持稳定。蒸馏水溶液可在 -20° 下保存长达 3 个月。
InChIInChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
InChIKeyVLSMHEGGTFMBBZ-OOZYFLPDSA-N
SMILESN1C[C@H](C(C)=C)[C@H](CC(O)=O)[C@H]1C(O)=O
常见问题列表
生物活性
Kainic acid 是 CNS 中兴奋性氨基酸受体亚型的有效激动剂。体内研究
Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. HO-I levels are significantly enhanced one, three and seven days after i.c.v, injection of Kainic acid. One day after i.c.v, injection of Kainic acid, the HO-I protein level reaches a maximum and then decreases, but is still significantly enhanced versus the vehicle-injected group. After i.c.v. injection of Kainic acid, HO-I-immunoreactivity is strongly induced not only in the CA3 but also widely in the whole hippocampus.