536759-91-8
中文名称
4,5,6,7-四氢-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯
英文名称
ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS
536759-91-8
分子式
C22H20N4O6
分子量
436.42
MOL 文件
536759-91-8.mol
更新日期
2024/05/06 09:38:41
536759-91-8 结构式
基本信息
中文别名
阿哌沙班杂质 G阿哌沙班杂质80S
进口资料代码-BMS-778960-01
4,5,6,7-四氢-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-
4,5,6,7-四氢-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸
1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-4,5,6,7-四氢-1H-吡唑啉[3,4-C]吡啶-3-羧酸乙酯
4,5,6,7-四氢-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯
4,5,6,7-四氢-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯(阿哌沙班中间体)
4,5,6,7-四氢-1-(4-甲氧基苯基)-6-(4-硝基苯基)-7-氧代-1H-吡唑并[3,4-C]吡啶-3-羧酸乙酯(阿哌沙班中间体) 10G
乙基 1H-吡唑并[3,4-C]吡啶-3 - 羧酸的酸,4,5,6,7 - 四氢-1 - (4 - 甲氧基苯基)-6 - (4 - 硝基苯基)-7 - 氧代乙基酯
英文别名
EOS-61014Apixaban iMpurityG
-6-(4-nitrophenyl)
Apixaban Impurity 80
Apixaban impurity BMS-589154
-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
所属类别
分析化学：对照品物理化学性质
熔点190-192°C
沸点658.7±55.0 °C(Predicted)
密度1.40
蒸气压0Pa at 25℃
储存条件Sealed in dry,Room Temperature
溶解度氯仿（微溶）、乙酸乙酯（微溶）
酸度系数(pKa)-3.80±0.20(Predicted)
形态固体
颜色浅棕色至浅橙色
InChIInChI=1S/C22H20N4O6/c1-3-32-22(28)19-18-12-13-24(14-4-6-16(7-5-14)26(29)30)21(27)20(18)25(23-19)15-8-10-17(31-2)11-9-15/h4-11H,3,12-13H2,1-2H3
InChIKeyRQNAOIQEGPVYTC-UHFFFAOYSA-N
SMILESC1(=O)N(C2=CC=C([N+]([O-])=O)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2
LogP3.59 at 23℃ and pH6.57
