DMA
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- CAS号:
- 188860-26-6
- 英文名:
- DMA
- 英文别名:
- 2,5'-Bi-1H-benzimidazole, 2'-(3,4-dimethoxyphenyl)-5-(4-methyl-1-piperazinyl)-;2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole;2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
- 中文名:
- DMA
- 中文别名:
- 2'-(3,4-二甲氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1'H-2,5'-联苯并[D]咪唑;2'-(3,4-二甲氧基苯基)-5-(4-甲基-1-哌嗪基)-2,5'-双[1H-苯并咪唑](DMA);2'-(3,4-二甲氧基苯基)-5-(4-甲基-1-哌嗪基)-2,5'-双[1H-苯并咪唑](DMA);2'-(3,4-二甲氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1'H-2,5'-联苯并[D]咪唑
- CBNumber:
- CB02666620
- 分子式:
- C27H28N6O2
- 分子量:
- 468.55
- MOL File:
- 188860-26-6.mol
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DMA化学性质
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熔点:
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220 °C
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沸点:
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737.3±70.0 °C(Predicted)
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密度:
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1.292±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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DMSO : ≥ 54 mg/mL (115.25 mM);
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形态:
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Powder
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酸度系数(pKa):
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10.78±0.10(Predicted)
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DMA性质、用途与生产工艺
DMA 是一种荧光化合物 (λex=340 nm, λem=478 nm)。
IC50: 3.4 μM (HeLa cell), 5.3 μM (MCF7 cell)
The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87) in comparison to Hoechst. In case of MCF7, the IC
50
is observed at 5.3 μM for DMA. The IC
50
determined in the case of HeLa is 3.4 μM for DMA.
DMA
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188860-26-6, DMA 相关搜索:
- 高端化学
- 2'-(3,4-二甲氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1'H-2,5'-联苯并[D]咪唑
- 2'-(3,4-二甲氧基苯基)-5-(4-甲基-1-哌嗪基)-2,5'-双[1H-苯并咪唑](DMA)
- 2'-(3,4-二甲氧基苯基)-5-(4-甲基-1-哌嗪基)-2,5'-双[1H-苯并咪唑](DMA)
- 2'-(3,4-二甲氧基苯基)-5-(4-甲基哌嗪-1-基)-1H,1'H-2,5'-联苯并[D]咪唑
- 188860-26-6
- 2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
- 2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
- 2,5'-Bi-1H-benzimidazole, 2'-(3,4-dimethoxyphenyl)-5-(4-methyl-1-piperazinyl)-