DHED
|
|
|
- CAS号:
- 549-02-0
- 英文名:
- 10β,17β-dihydroxyestra-1,4-dien-3-one
- 英文别名:
- 10β;DHED;4-dien-3-one;17β-dihydroxyestra-1;10β,17β-dihydroxyestra-1,4-dien-3-one;10β,17β-dihydroxyestra-1,4-dien-3-one;10,17β-Dihydroxy-estra-1,4-dien-3-one;Estra-1,4-dien-3-one, 10,17-dihydroxy-, (17β)-;10β,17β dihydroxyestra 1,4 dien 3 one,10β,17βdihydroxyestra1,4dien3one
- 中文名:
- DHED
- 中文别名:
- 化合物 T10036
- CBNumber:
- CB03037801
- 分子式:
- C18H24O3
- 分子量:
- 288.39
- MOL File:
- 549-02-0.mol
|
|
|
DHED化学性质
-
熔点:
-
217-219 °C(Solv: ethyl acetate (141-78-6))
-
|
-
沸点:
-
485.3±45.0 °C(Predicted)
-
|
-
密度:
-
1.24±0.1 g/cm3(Predicted)
-
|
-
储存条件:
-
2-8°C
-
|
-
酸度系数(pKa):
-
12.35±0.60(Predicted)
-
|
-
形态:
-
powder
-
|
-
颜色:
-
white to light brown
-
|
-
旋光性 (optical activity):
-
[α]/D -20 to -30°, c = 1 in methanol
-
|
DHED性质、用途与生产工艺
10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) 是一种靶向大脑的雌激素 (estrogen) 前体。10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) 是 17β-estradiol 的主要生物前药，可降低脑部温度调节功能障碍的大鼠发生潮热。
10β,17β-dihydroxyestra-1,4-dien-3-one (DHED), is an inactive bioprecursor prodrug of 17β-estradiol converting to 17β-estradiol only in the brain. DHED as an E2-bioprecursor may be a viable approach for delivering E2 selectively into the brain for the potential treatment of hot flushes.
DHED
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-128976 | DHED
10β,17β-dihydroxyestra-1,4-dien-3-one | 549-02-0 | 5mg | 800元 |
| 2024/04/30 | HY-128976 | DHED
10β,17β-dihydroxyestra-1,4-dien-3-one | 549-02-0 | 10mM * 1mLin DMSO | 880元 |
549-02-0, DHED 相关搜索:
- 化合物 T10036
- 549-02-0
- 10β,17β dihydroxyestra 1,4 dien 3 one,10β,17βdihydroxyestra1,4dien3one
- 4-dien-3-one
- 17β-dihydroxyestra-1
- 10β,17β-dihydroxyestra-1,4-dien-3-one
- 10β
- 10,17β-Dihydroxy-estra-1,4-dien-3-one
- Estra-1,4-dien-3-one, 10,17-dihydroxy-, (17β)-
- DHED
- 10β,17β-dihydroxyestra-1,4-dien-3-one