MLS-573151
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- CAS号:
- 10179-57-4
- 英文名:
- MLS-573151
- 英文别名:
- MLS-573151;4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide;Benzenesulfonamide, 4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-;MLS-573151,granulocytes,Inhibitor,Ras,inhibit,MLS-000573151,MLS 000573151,GTPase,MLS 573151,Cdc42,MLS573151,MLS000573151
- 中文名:
- MLS-573151
- 中文别名:
- 化合物MLS-573151;4-(3,5-二苯基-4,5-二氢-1H-吡唑-1-基)苯磺酰胺
- CBNumber:
- CB03152689
- 分子式:
- C21H19N3O2S
- 分子量:
- 377.46
- MOL File:
- 10179-57-4.mol
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MLS-573151化学性质
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储存条件:
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RT
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溶解度:
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Soluble in DMSO (up to 20 mg/ml).
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形态:
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solid
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颜色:
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Yellow
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稳定性:
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Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
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MLS-573151性质、用途与生产工艺
MLS-573151 (MLS000573151) 是一种选择性 GTPase Cdc42 的抑制剂，EC50 为 2 μM。MLS-573151 对其他 GTPases 家族成员无效，例如 Rab2，Rab7，H-Ras，Rac1，Rac 2 和 RhoA 野生型。MLS-573151 通过阻止 GTP 与 Cdc42 的结合来发挥作用。
The fluorescence intensities of phagocytosed beads or bacteria in hemocytes, taken as a measure of phagocytosis efficiency, were markedly reduced in granulocytes treated with MLS-573151 (50 μM; for 15 min) compared to that in the control group. MLS-573151 could effectively inhibit the phagocytic ability of granulocytes.
MLS-573151
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-113849 | MLS-573151 | | 1 mg | 400元 |
| 2024/04/30 | HY-113849 | MLS-573151
MLS-573151 | 10179-57-4 | 10mM * 1mLin DMSO | 1100元 |
10179-57-4, MLS-573151 相关搜索:
- 药靶配体
- 4-(3,5-二苯基-4,5-二氢-1H-吡唑-1-基)苯磺酰胺
- 化合物MLS-573151
- 10179-57-4
- MLS-573151,granulocytes,Inhibitor,Ras,inhibit,MLS-000573151,MLS 000573151,GTPase,MLS 573151,Cdc42,MLS573151,MLS000573151
- 4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide
- Benzenesulfonamide, 4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-
- MLS-573151