化合物T7747
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- CAS号:
- 157000-76-5
- 英文名:
- Datelliptium chloride hydrochloride
- 英文别名:
- Datelliptium chloride hydrochloride;antitumoral,Datelliptium chloride hydrochloride,DNA/RNA Synthesis,activity,Inhibitor,Ellipticine,hepatotoxicity,inhibit,Datelliptium chloride,antineoplastic
- 中文名:
- 化合物T7747
- 中文别名:
- 化合物T7747
- CBNumber:
- CB15985310
- 分子式:
- C23H28ClN3O
- 分子量:
- 397.95
- MOL File:
- 157000-76-5.mol
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化合物T7747性质、用途与生产工艺
Datelliptium chloride hydrochloride 是一种由 Ellipticine (HY-15753) 衍生的 DNA 嵌合剂。Datelliptium chloride hydrochloride 在体内对多种小鼠实体瘤有效。
Datelliptium chloride hydrochloride shows cytotoxic effects after 2 hours of treatment in suspension and primary cultures of rat hepatocytes.
Datelliptium chloride hydrochloride has broad antitumor activity against solid tumors of mice in vivo.
Datelliptium chloride hydrochloride (170 mg/kg; i.v; for 12 days) exhibits a high degree of antitumor activity at early staged disease.
Datelliptium chloride hydrochloride is selectively cytotoxic for solid tumors over leukemia L1210.
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Animal Model:
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Mice, colon adenocarcinoma early staged disease model
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Dosage:
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170 mg/kg
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Administration:
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Intravenous injection, for 12 days
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Result:
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Highly active against colon adenocarcinoma.
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化合物T7747
上下游产品信息
上游原料
下游产品
157000-76-5, 化合物T7747 相关搜索:
- 高端化学
- 标准品
- 化合物T7747
- 157000-76-5
- antitumoral,Datelliptium chloride hydrochloride,DNA/RNA Synthesis,activity,Inhibitor,Ellipticine,hepatotoxicity,inhibit,Datelliptium chloride,antineoplastic
- Datelliptium chloride hydrochloride