OMACICLOVIR
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- CAS号:
- 124265-89-0
- 英文名:
- OMaciclovir
- 英文别名:
- H2G;H 2G;ABT091;ABT-091;ABT 091;(-)-2HM-HBG;6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-
- 中文名:
- OMACICLOVIR
- 中文别名:
- 化合物 T28234
- CBNumber:
- CB22611437
- 分子式:
- C10H15N5O3
- 分子量:
- 253.26
- MOL File:
- 124265-89-0.mol
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OMACICLOVIR化学性质
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密度:
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1.68±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 230 mg/mL (908.16 mM)
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酸度系数(pKa):
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9.61±0.20(Predicted)
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OMACICLOVIR性质、用途与生产工艺
Omaciclovir (H2G) 是一种有效的选择性疱疹病毒 herpesvirus 复制抑制剂。Omaciclovir 是一种核苷类似物。
Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys.
Omaciclovir shows antiviral activities against different human herpesviruses with EC
50
s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively.
OMACICLOVIR
上下游产品信息
上游原料
下游产品
124265-89-0, OMACICLOVIR 相关搜索:
- 化合物 T28234
- 124265-89-0
- 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-
- (-)-2HM-HBG
- ABT 091
- ABT091
- ABT-091
- H 2G
- H2G