BIS-PEG2-PFP ESTER
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- CAS号:
- 1314378-18-1
- 英文名:
- Bis-PEG2-PFP ester
- 英文别名:
- PFP-PEG2-PFP;PEG2 BIS-PFP ESTER;Bis-PEG2-PFP ester;Bis-dPEG??-PFP ester;Ethyleneglycol-1,2-bis(pentafluorophenyl 3-oxypropionate);Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-, 1,1'-bis(2,3,4,5,6-pentafluorophenyl) ester
- 中文名:
- BIS-PEG2-PFP ESTER
- 中文别名:
- 双-聚乙二醇-PFP酯
- CBNumber:
- CB23062410
- 分子式:
- C20H12F10O6
- 分子量:
- 538.29
- MOL File:
- 1314378-18-1.mol
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BIS-PEG2-PFP ESTER性质、用途与生产工艺
NH2-PEG3-BOC 是一种不可降解 (non-cleavable) 的含 2 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。Bis-PEG2-PFP ester 也是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
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PEGs
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Alkyl/ether
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Non-cleavable
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ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
BIS-PEG2-PFP ESTER
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1314378-18-1, BIS-PEG2-PFP ESTER 相关搜索:
- C20H12F10O6
- 双-聚乙二醇-PFP酯
- 1314378-18-1
- Bis-dPEG??-PFP ester
- Ethyleneglycol-1,2-bis(pentafluorophenyl 3-oxypropionate)
- Propanoic acid, 3,3'-[1,2-ethanediylbis(oxy)]bis-, 1,1'-bis(2,3,4,5,6-pentafluorophenyl) ester
- PEG2 BIS-PFP ESTER
- PFP-PEG2-PFP
- Bis-PEG2-PFP ester