西咪替丁亚砜盐酸盐
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- CAS号:
- 54237-72-8
- 英文名:
- CIMETIDINE SULPHOXIDE DIHYDROCHLORIDE
- 英文别名:
- SKF-92452;Cimetidine S-oxide;cimetidine sulfoxide;Cimetidine impurity E;Cimetidine sulphoxide;Cimetidine EP Impurity E;Cimetidine Impurity E(EP);2-Cyano-1-methyl-3-[2-[[(5-methyl-1;Cimetidine Hydrochloride Impurity E;CIMETIDINE SULPHOXIDE DIHYDROCHLORIDE
- 中文名:
- 西咪替丁亚砜盐酸盐
- 中文别名:
- 西咪替丁亚砜;西咪替丁杂质E;西咪替丁EP杂质E;西咪替丁亚砜盐酸盐;西咪替丁杂质E(EP);)-西咪替丁 S-氧化物;(±)-西咪替丁 S-氧化物;西咪替丁杂质E(EP) 标准品;西咪替丁EP杂质E(西咪替丁亚砜);西咪替丁杂质5(西咪替丁EP杂质E)
- CBNumber:
- CB2836704
- 分子式:
- C10H16N6OS
- 分子量:
- 268.34
- MOL File:
- 54237-72-8.mol
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西咪替丁亚砜盐酸盐化学性质
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熔点:
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>180°C (dec.)
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沸点:
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594.8±60.0 °C(Predicted)
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密度:
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1.39±0.1 g/cm3(Predicted)
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储存条件:
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-20°C Freezer
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溶解度:
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DMSO (Slightly, Heated), Methanol (Slightly)
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形态:
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Solid
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酸度系数(pKa):
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13.38±0.10(Predicted)
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颜色:
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White to Off-White
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西咪替丁亚砜盐酸盐性质、用途与生产工艺
Cimetidine sulfoxide (Cimetidine sulphoxide) 是一种 Cimetidine 的亚砜代谢产物。Cimetidine 是一种组胺 H2 受体 (H2-receptor) 拮抗剂，可用于消化性溃疡和上消化道出血的研究。
Active transport of Cimetidine across the rat small intestine is observable at lower substrate concentrations (40 and 200 μM), but is masked by passive transfer at higher concentrations (400 μM). Cimetidine sulfoxide is detected after some incubations.
The enantiomeric composition of Cimetidine sulfoxide is also determined in rat urine (24 h) following the administration of Cimetidine (30 mg/kg; po) to male Wistar rats. The enantiomeric ratio in this case is found to be (+/−) 57:43.
西咪替丁亚砜盐酸盐
上下游产品信息
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-136338 | Cimetidine sulfoxide | | 5 mg | 1500元 |
| 2024/04/30 | HY-136338 | 西咪替丁亚砜盐酸盐
Cimetidine sulfoxide | 54237-72-8 | 10mg | 2400元 |
54237-72-8, 西咪替丁亚砜盐酸盐 相关搜索:
- Heterocycles, Metabolites & Impurities, Sulfur & Selenium Compounds
- 高端化学
- 标准品
- 对照品
- 杂质对照品
- 医药原料
- 西咪替丁杂质5(西咪替丁EP杂质E)
- 西咪替丁EP杂质E(西咪替丁亚砜)
- 1-氰基-3-甲基-2-(2-(((4-甲基-1H-咪唑-5-基)甲基)亚磺酰基)乙基)胍
- 西咪替丁杂质E
- 西咪替丁杂质E(EP) 标准品
- 西咪替丁杂质E(EP)
- 西咪替丁亚砜
- 西咪替丁EP杂质E
- (±)-西咪替丁 S-氧化物
- )-西咪替丁 S-氧化物
- 西咪替丁亚砜盐酸盐
- 54237-72-8
- Cimetidine sulphoxide
- Cimetidine Hydrochloride EP Impurity E
- Cimetidine Hydrochloride Impurity E
- 1-Cyano-3-methyl-2-(2-(((4-methyl-1H-imidazol-5-yl)methyl)sulfinyl)ethyl)guanidine
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]sulfinyl]ethyl]-
- 2-Cyano-1-methyl-3-[2-[[(5-methyl-1
- Cimetidine impurity 5/Cimetidine EP Impurity E/Cimetidine Sulfoxide /2-Cyano-1-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfinyl]-ethyl]guanidine
- CIMETIDINE EP IMPURITY E (CIMETIDINE SULPHOXIDE)
- Cimetidine Impurity 5（Cimetidine EP Impurity E）
- Cimetidine Impurity E(EP)
- Cimetidine impurity E
- N-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylsulphinyl]ethyl]guanidine
- Cimetidine EP Impurity E
- 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfinyl]ethyl]guanidine
- SKF-92452
- Cimetidine S-oxide
- 2-Cyano-1-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfinyl]ethyl]guanidine
- 1-Cyano-3-methyl-2-[2-[[(5-methyl-1H-imidazole-4-yl)methyl]sulfinyl]ethyl]guanidine
- 1-[2-[(5-Methyl-1H-imidazole-4-yl)methylsulfinyl]ethyl]-3-methyl-2-cyanoguanidine
- cimetidine sulfoxide
- CIMETIDINE SULPHOXIDE DIHYDROCHLORIDE