T4磺酸酯
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- CAS号:
- 77074-49-8
- 英文名:
- O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine
- 英文别名:
- Thyroxine sulfate;T4 Sulfate;L-Thyroxine sulfate;Thyroxine 4'-O-Sulfate;L-Thyroxine sulfate salt;Thyroxine Hydrogen Sulfate;O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine;L-Tyrosine, O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo-
- 中文名:
- T4磺酸酯
- 中文别名:
- T4磺酸酯;甲状腺素硫酸;硫酸L-甲状腺素;L-甲状腺素硫酸盐;化合物 T20557
- CBNumber:
- CB31236409
- 分子式:
- C15H11I4NO7S
- 分子量:
- 856.93
- MOL File:
- 77074-49-8.mol
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T4磺酸酯化学性质
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密度:
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2.658±0.06 g/cm3(Predicted)
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储存条件:
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Store at 4°C
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溶解度:
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DMSO : ≥ 31 mg/mL (36.18 mM)
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酸度系数(pKa):
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-4.80±0.18(Predicted)
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T4磺酸酯性质、用途与生产工艺
Thyroxine sulfate是甲状腺激素代谢物。
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Human Endogenous Metabolite
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Thyroxine sulfate (T4S) is a normal component of human serum and amniotic fluid, and it is mostly derived from thyroxine peripherally and accumulates when type I 5-monodeiodinating activity is low in fetuses or inhibited by drugs, such as ipodate.
Significant amounts of thyroxine sulfate (T4S) in fetal sheep serum, meconium, bile, and amniotic and allantoic fluids are observed. T4S concentration in amniotic fluid from women at 18-19 weeks of gestation (25.5 ng/dL) is higher than that at 14-15 weeks of gestation (14.3 ng/dL). A significant rise in serum T4S is detected in hyperthyroid patients 1 day after ingestion of 1 g of ipodate. Thyroxine undergoes significant sulfation in rats, and biliary excretion of T4S is enhanced if its type I deiodination is inhibited. Serum T4S levels are clearly elevated compared with healthy references, and the decreased deiodination by liver D1 during critical illness appears to play a role in this increase in serum T4S levels.
T4磺酸酯
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-101406 | T4磺酸酯
Thyroxine sulfate | 77074-49-8 | 5mg | 800元 |
| 2024/04/30 | HY-101406 | T4磺酸酯
Thyroxine sulfate | | 10 mg | 1300元 |
77074-49-8, T4磺酸酯 相关搜索:
- Sulfur & Selenium Compounds
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Aromatics
- C15H11I4NO7S
- 化合物 T20557
- L-甲状腺素硫酸盐
- 硫酸L-甲状腺素
- 甲状腺素硫酸
- T4磺酸酯
- 77074-49-8
- Thyroxine sulfate
- T4 Sulfate
- L-Thyroxine sulfate salt
- L-Tyrosine, O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo-
- L-Thyroxine sulfate
- Thyroxine Hydrogen Sulfate
- Thyroxine 4'-O-Sulfate
- O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine