TONABERSAT
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- CAS号:
- 175013-84-0
- 英文名:
- TONABERSAT
- 英文别名:
- SB 22045;SB 220453;TONABERSAT;SB 220453;SB220453;Tonabersat [ban, inn];Tonabersat (SB-220453);Tonabersat >=98% (HPLC);SB-220453;SB 220453;SB220453;N-((3S,4S)-6-Acetyl-3-hydroxy-2,2-diMethylchroMan-4-yl)-3-chloro-4-fluorobenzaMide;2H-Benzo(B)pyran-3-ol, 6-acetyl-4-(3-chloro-4-fluorobenzoylamino)-3,4-dihydro-2,2-dimethyl-
- 中文名:
- TONABERSAT
- 中文别名:
- 托那博沙;N-((3S,4S)-6-乙酰基-3-羟基-2,2-二甲基苯并二氢吡喃-4-基)-3-氯-4-氟苯甲酰胺;N-[(3S,4S)-6-乙酰基-3,4-二氢-3-羟基-2,2-二甲基-2H-1-苯并吡喃-4-基]-3-氯-4-氟苯甲酰胺
- CBNumber:
- CB3406968
- 分子式:
- C20H19ClFNO4
- 分子量:
- 391.82
- MOL File:
- 175013-84-0.mol
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TONABERSAT化学性质
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沸点:
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554.5±50.0 °C(Predicted)
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密度:
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1.38
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储存条件:
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2-8°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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11.86±0.60(Predicted)
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形态:
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powder
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颜色:
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white to beige
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旋光性 (optical activity):
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[α]/D -100 to -110°, c = 1 in methanol
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TONABERSAT性质、用途与生产工艺
Tonabersat (SB-220453) 是一种 gap-junction 调节剂。Tonabersat Tonabersat 预防中枢神经系统的炎症损伤。
Tonabersat, a novel benzopyran derivative, inhibits cortical spreading depression (CSD) and therefore might be able to inhibit the early migraine mechanisms.
Treatment with Tonabersat (10 mg/kg) significantly inhibits progression of metastatic lesions. Addition of NSC 241240 to either agent profoundly inhibits brain metastasis.
TONABERSAT
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-15204 | Tonabersat | | 1 mg | 718元 |
| 2024/04/30 | HY-15204 | TONABERSAT
Tonabersat | 175013-84-0 | 5mg | 1581元 |
175013-84-0, TONABERSAT 相关搜索:
- Inhibitors
- Heterocycles
- Aromatics
- Aromatics Compounds
- C20H19ClFNO4
- N-((3S,4S)-6-乙酰基-3-羟基-2,2-二甲基苯并二氢吡喃-4-基)-3-氯-4-氟苯甲酰胺
- 托那博沙
- N-[(3S,4S)-6-乙酰基-3,4-二氢-3-羟基-2,2-二甲基-2H-1-苯并吡喃-4-基]-3-氯-4-氟苯甲酰胺
- 175013-84-0
- N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-3-chloro-4-fluorobenzamide
- SB 220453;SB220453
- SB-220453;SB 220453;SB220453
- Tonabersat >=98% (HPLC)
- Benzamide, N-[(3S,4S)-6-acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3-chloro-4-fluoro-
- Tonabersat (SB-220453)
- N-((3S,4S)-6-Acetyl-3-hydroxy-2,2-diMethylchroMan-4-yl)-3-chloro-4-fluorobenzaMide
- Tonabersat [ban, inn]
- 2H-Benzo(B)pyran-3-ol, 6-acetyl-4-(3-chloro-4-fluorobenzoylamino)-3,4-dihydro-2,2-dimethyl-
- SB 220453
- SB 22045
- N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3- chloro-4-fluoro-benzamide
- TONABERSAT