15D-PGJ2
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- CAS号:
- 87893-55-8
- 英文名:
- 15D-PGJ2
- 英文别名:
- 15D-PGJ2;15d-PGJ?;15-deoxy-Δ-12;15-deoxy-Δdelta12,14-Pgj 2;15-Deoxy-Delta12;14-Prostaglandin J2;15-Deoxy-Δ12,14-PGJ2;12,14-prostaglandin J2;15-DEOXY-DELTA12,14-PGJ2
- 中文名:
- 15D-PGJ2
- 中文别名:
- 化合物 T22473;15-脱氧-Δ12,14-前列腺素 J2;15-DEOXY-Δ12,14-PROSTAGLANDIN J2;(5Z,12E,14E)-11-氧代-前列腺-5,9,12,14-四烯-1-酸
- CBNumber:
- CB5206904
- 分子式:
- C20H28O3
- 分子量:
- 316.43
- MOL File:
- 87893-55-8.mol
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15D-PGJ2化学性质
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闪点:
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-9℃
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储存条件:
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-20°C
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溶解度:
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Soluble in Methyl acetate (supplied pre-dissolved - 1mg/ml)
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形态:
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methyl acetate solution
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15D-PGJ2性质、用途与生产工艺
15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) 是一种环戊烯酮前列腺素和 PGD2 的代谢产物。15-Deoxy-Δ-12,14-prostaglandin J2 是一种选择性的 PPARγ (EC50 为 2 µM) 和共价的 PPARδ 激动剂。15-Deoxy-Δ-12,14-prostaglandin J2 促进 C3H10T1/2 成纤维细胞向脂肪细胞的有效分化，EC50 为 7 μM。
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PPARγ
2 μM (EC
50
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PPARδ
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Human Endogenous Metabolite
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15-Deoxy-Δ12,14-PGJ2 (15d-PGJ2) is a cyclopentenone prostaglandin that features an electrophilic, α, β-unsaturated ketone (an enone) in the cyclopentenone ring. 15-Deoxy-Δ-12,14-prostaglandin J2 is one of the cyPGs whose functions in inflammation, cell proliferation, survival, and apoptosis have been documented. 15-Deoxy-Δ-12,14-prostaglandin J2 activates PPARδ in a dose-dependent manner. 15-Deoxy-Δ-12,14-prostaglandin J2 activates PPARδ’s transcriptional activity through formation of a covalent adduct between its endocyclic enone at C9 and Cys249 in the receptor’s ligand-binding domain.
15D-PGJ2
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15D-PGJ2
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15D-PGJ2国内生产厂家
87893-55-8, 15D-PGJ2 相关搜索:
- 生化试剂
- (5Z,12E,14E)-11-氧代-前列腺-5,9,12,14-四烯-1-酸
- 15-DEOXY-Δ12,14-PROSTAGLANDIN J2
- 15-脱氧-Δ12,14-前列腺素 J2
- 化合物 T22473
- 87893-55-8
- 15-Deoxy-Delta12
- 15-deoxy-Δ12,14-Prostaglandin J2 MaxSpec Standard
- 15deoxyΔ12,14Prostaglandin J2,15 deoxy Δ 12,14 Prostaglandin J2,15-deoxy-Δ-12,14-Prostaglandin J-2
- 15-deoxy-Δ-12
- 14-Prostaglandin J2
- 15d-PGJ - CAS 87893-55-8 - Calbiochem
- 15-deoxy-&Delta
- 12,14-prostaglandin J2
- 15-deoxy-12,14-Prostaglandin J2 MaxSpecStandard
- Prosta-5,9,12,14-tetraen-1-oic acid, 11-oxo-, (5Z,12E,14E)- (9ci)
- Prosta-5,9,12,14-tetraen-1-oic acid, 11-oxo-, (5Z,12E,14E)-
- delta12,14-Pgj 2
- 15-Deoxy-delta12,14-prostaglandin
- 15D-PGJ2 (15-DEOXY-DELTA12,14-PROSTAGLANDIN J2)
- (Z)-7-[(1S,5E)-5-[(E)-oct-2-enylidene]-4-oxo-1-cyclopent-2-enyl]hept-5-enoic acid
- 15-Deoxy-D-12,14-prostaglandin J2
- 15-Deoxy-delta-12-delta-14-prostaglandinej2
- PROSTAGLANDIN J2, 15-DEOXY-DELTA12,14
- (5Z,12E,14E)-11-OXO-PROSTA-5,9,12,14-TETRAEN-1-OIC ACID
- 11-OXO-PROSTA-5Z,9,12E,14Z-TETRAEN-1-OIC
- 15-DEOXY-DELTA-12,14-PROSTAGLANDIN J2
- 15-DEOXY-DELTA12,14-PGJ2
- 15-DEOXY-DELTA12,DELTA14-PROSTAGLANDIN J2
- 15-DEOXY-DELTA12,14-PROSTAGLANGIN J2
- 15D-PGJ2
- 15d-PGJ?
- 15-deoxy-Δ12,14-Prostaglandin J2 solution
- 15-Deoxy-Δ12,14-PGJ2
- 11-Oxoprosta-(5Z,9,12E,14E)-tetraen-1-oic acid
- 15-deoxy-Δ12,14-Prostaglandin J2 Lipid Maps MS Standard