Bis-peg10-nhs ester
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- CAS号:
- 2221949-02-4
- 英文名:
- Bis-peg10-nhs ester
- 英文别名:
- Di-NHS Ester-PEG10;4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid, 1,34-bis(2,5-dioxo-1-pyrrolidinyl) ester
- 中文名:
- Bis-peg10-nhs ester
- 中文别名:
- 琥珀酰亚胺酯-十聚乙二醇-琥珀酰亚胺酯
- CBNumber:
- CB66126504
- 分子式:
- C32H52N2O18
- 分子量:
- 752.76
- MOL File:
- 2221949-02-4.mol
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Bis-peg10-nhs ester性质、用途与生产工艺
Bis-PEG10-NHS ester 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。Bis-PEG10-NHS ester 可用于合成一系列 PROTAC 分子。Bis-PEG10-NHS ester 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
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PEGs
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Alkyl/ether
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Cleavable
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Bis-peg10-nhs ester
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2221949-02-4, Bis-peg10-nhs ester 相关搜索:
- C32H52N2O18
- 琥珀酰亚胺酯-十聚乙二醇-琥珀酰亚胺酯
- 2221949-02-4
- Di-NHS Ester-PEG10
- 4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid, 1,34-bis(2,5-dioxo-1-pyrrolidinyl) ester