Katacalcin TFA
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- CAS号:
- 英文名:
- Katacalcin TFA
- 英文别名:
- Katacalcin TFA
- 中文名:
- Katacalcin TFA
- 中文别名:
- 钙抑肽,人;钙抑肽三氟乙酸盐
- CBNumber:
- CB75419758
- 分子式:
- C??H???F?N??O??S?
- 分子量:
- 0
- MOL File:
- Mol file
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Katacalcin TFA性质、用途与生产工艺
Katacalcin TFA (PDN 21 TFA) 是一种有效的具有降低血钙效应的多肽激素。
Katacalcin is a potent plasma calcium lowering peptide. Katacalcin belongs to the calcitonin family, that causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of these ions in the bones. Katacalcin (KC) belongs to a small family of polypeptides that are encoded by the calc-1 gene and also include calcitonin (CT) and procalcitonin NH2-terminal cleavage peptide (N-ProCT). Katacalcin pretreatment leads to a concentration-dependent decrease at concentrations between 1 amol/liter and 10 fmol/liter and is a more potent inhibitor of fMLP-induced chemotaxis than CT or procalcitonin (PCT). Katacalcin deactivates CD14
+
peripheral blood mononuclear cell (PBMC) chemotaxis not only toward N-formyl-Met-Leu-Phe (fMLP) but also toward other attractants of the chemokine family (heterologous deactivation) as well as toward PCT and CT. Pretreatment of CD14
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PBMCs with Katacalcin also deactivates subsequent chemotaxis toward Katacalcin itself. Katacalcin elicites concentration-dependent migration of CD14
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PBMC at concentrations from the atomolar to the micromolar range and deactivates attractant-induced chemotaxis. Katacalcin regulates human CD14
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PBMC migration via signaling events involving protein kinase A-dependent cAMP pathways.
Katacalcin TFA
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Katacalcin TFA 试剂级价格
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/01/25 | HY-P0149A | Katacalcin TFA Katacalcin TFA | | 500μg | 1600元 |
2024/01/25 | HY-P0149A | Katacalcin TFA Katacalcin TFA | | 1mg | 2600元 |
Katacalcin TFA 相关搜索:
- 钙抑肽,人
- 钙抑肽三氟乙酸盐
- Katacalcin TFA