黄芩黄酮II
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- CAS号:
- 55084-08-7
- 英文名:
- NEOBAICALEIN
- 英文别名:
- NEOBAICALEIN;Skullcapflavone Ⅱ;Skullcapflavon II;SKULLCAPFLAVONE II;scullcapflavone II;Skullcapflavone II >=90% (LC/MS-UV);2',5-Dihydroxy-6,6',7,8-tetramethoxyflavone;4H-1-Benzopyran-4-one, 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-;inhibit,inflammatory,Skullcapflavone II,Bacterial,antimicrobial,mycobacterial,differentiation,Inhibitor,osteoclast,flavonoid
- 中文名:
- 黄芩黄酮II
- 中文别名:
- 黄芩新素;黄芩黄酮Ⅱ;黄芩新素Ⅱ;黄芩黄酮II;黄芩新素II;美黄芩黄酮II;黄芩新素II(美黄芩黄酮II)
- CBNumber:
- CB8233473
- 分子式:
- C19H18O8
- 分子量:
- 374.34
- MOL File:
- 55084-08-7.mol
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黄芩黄酮II化学性质
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沸点:
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636.9±55.0 °C(Predicted)
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密度:
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1.375±0.06 g/cm3(Predicted)
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溶解度:
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Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
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形态:
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powder
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酸度系数(pKa):
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6.81±0.40(Predicted)
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颜色:
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Yellow
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黄芩黄酮II性质、用途与生产工艺
黄芩为唇形科多年生草本。其有效成分为黄芩素、黄芩甙、汉黄芩素、黄芩新素等5种黄酮成分。此外，还含有β-谷甾醇、苯甲酸、黄芩酶等。有抑菌、抗病毒、镇静、利尿、保肝、保胆、解毒、消炎及使血糖上升等作用。主要用于治疗烂鳃病、疖疮病、打印病、出血性败血症、肠炎病等。
Skullcapflavone II 是从黄芩中提取的黄酮类化合物，具有抗炎、抗菌作用。Skullcapflavone II 调节破骨细胞的分化、存活和功能。Skullcapflavone II 对 M. aurum 和M. bovis BCG 具有较强的抗菌活性。
Skullcapflavone II inhibits osteoclastogenesis with decreased activation of MAPKs, Src, and cAMP response element-binding protein (CREB), which have been known to be redox sensitive. Skullcapflavone II decreases reactive oxygen species by scavenging them or activating nuclear factor-erythroid 2-related factor 2 (Nrf2), and its effects were partially reversed by hydrogen peroxide cotreatment or Nrf2 deficiency.
Skullcapflavone II, a potential bradykinin antagonist, reduces the major pathophysiological features of allergic asthma, at least in part by acting on TGF-β1/Smad signaling pathways.
化学性质
白色结晶，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于五味子。
黄芩黄酮II
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-N6624 | 黄芩黄酮II
Skullcapflavone II | 55084-08-7 | 1mg | 1050元 |
| 2024/04/30 | HY-N6624 | 黄芩黄酮II
Skullcapflavone II | 55084-08-7 | 5mg | 2700元 |
55084-08-7, 黄芩黄酮II 相关搜索:
7,8-二甲氧基黄酮 2,3,4-三甲氧基-6-甲基苯酚 2,3,4-三甲氧基苯甲醛 2,3-二甲氧基-5-甲基-1,4-苯二酚 2,3,4-三甲氧基苯酚 5,7,8-三羟基黄酮 2,3,4,5-四甲氧基甲苯 汉黄芩素 1,2,3,4-四甲氧基苯
- Hexa-substituted Flavones
- 化合物
- 标准品 -中药标准品
- 对照品
- 黄芩黄酮Ⅱ
- 黄芩新素Ⅱ
- 黄芩新素II(美黄芩黄酮II)
- 美黄芩黄酮II
- 黄芩新素II
- 黄芩新素
- 黄芩黄酮II
- 55084-08-7
- inhibit,inflammatory,Skullcapflavone II,Bacterial,antimicrobial,mycobacterial,differentiation,Inhibitor,osteoclast,flavonoid
- Skullcapflavone II >=90% (LC/MS-UV)
- 4H-1-Benzopyran-4-one, 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-
- NEOBAICALEIN
- SKULLCAPFLAVONE II
- scullcapflavone II
- Skullcapflavone Ⅱ
- Skullcapflavon II
- 2',5-Dihydroxy-6,6',7,8-tetramethoxyflavone