AX 20017
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- CAS号:
- 329221-38-7
- 英文名:
- AX 20017
- 英文别名:
- AX 20017;PknG Inhibitor;AX-20017; AX 20017;AX 20017,AX20017,Inhibitor,Bacterial,inhibit,AX-20017;2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide;Benzo[b]thiophene-3-carboxamide, 2-[(cyclopropylcarbonyl)amino]-4,5,6,7-tetrahydro-
- 中文名:
- AX 20017
- 中文别名:
- 化合物AX20017;2-(环丙烷甲酰氨基)-4,5,6,7-四氢苯并[B]噻吩-3-甲酰胺
- CBNumber:
- CB82627353
- 分子式:
- C13H16N2O2S
- 分子量:
- 264.34
- MOL File:
- 329221-38-7.mol
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AX 20017化学性质
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储存条件:
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under inert gas (nitrogen or Argon) at 2–8 °C
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溶解度:
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DMSO : ≥ 32 mg/mL (121.06 mM)
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AX 20017性质、用途与生产工艺
AX20017是蛋白激酶G (PknG) 的小分子抑制剂，IC50 值为 0.39 μM。
The compound AX20017 inhibitor is bound deep within a narrow pocket formed by the inter lobe cleft of the PknG domain. The main chain Glu233:O and Val235:NH of PknG form hydrogen bonds with AX20017.AX20017 results in mycobacterial transfer to lysosomes and killing of the mycobacteria. AX20017 does not affect the human kinases, whereas the activity of PknG is effectively inhibited. AX20017 does not affect cellular morphology, membrane ruffling, or macropinocytosis.
AX 20017
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-14987 | AX 20017
AX20017 | 329221-38-7 | 5mg | 500元 |
| 2024/04/30 | HY-14987 | AX 20017
AX20017 | 329221-38-7 | 10mg | 700元 |
329221-38-7, AX 20017 相关搜索:
- 抑制剂
- 化合物AX20017
- 2-(环丙烷甲酰氨基)-4,5,6,7-四氢苯并[B]噻吩-3-甲酰胺
- 329221-38-7
- AX 20017,AX20017,Inhibitor,Bacterial,inhibit,AX-20017
- Benzo[b]thiophene-3-carboxamide, 2-[(cyclopropylcarbonyl)amino]-4,5,6,7-tetrahydro-
- AX-20017; AX 20017
- 2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
- PknG Inhibitor
- AX 20017