1338780-86-1
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- CAS号:
- 1338780-86-1
- 英文名:
- AU1235
- 英文别名:
- AU1235;AU1235;AU-1235;AU 1235;Urea, N-tricyclo[3.3.1.13,7]dec-1-yl-N'-(2,3,4-trifluorophenyl)-;Inhibitor,MmpL3,transport,tuberculosis,AU1235,cell,AU 1235,AU-1235,synthesis,inhibit,Bacterial,wall,Mycobacterium
- 中文名:
- 1338780-86-1
- 中文别名:
- 化合物AU1235;结核分枝杆菌金刚烷脲尿素抑制剂(AU1235)
- CBNumber:
- CB83309531
- 分子式:
- C17H19F3N2O
- 分子量:
- 324.34
- MOL File:
- 1338780-86-1.mol
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1338780-86-1化学性质
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沸点:
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377.7±42.0 °C(Predicted)
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密度:
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1.33±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO : 6 mg/mL (18.50 mM)
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酸度系数(pKa):
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12.02±0.70(Predicted)
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1338780-86-1性质、用途与生产工艺
AU1235 是一种金刚烷基尿素，是 Mycobacterium tuberculosis 蛋白 MmpL3 的有效抑制剂。
AU1235 is similarly active against MDR isolates of
M. tb
displaying resistance to isoniazid, rifampicin, and pyrazinamide in addition to streptomycin, fluoroquinolones and/or ethambutol. AU1235 also inhibits
Mycobacterium smegmatis
and
Mycobacterium fortuitum
although the MICs (3.2 to 6.4 μg/ml) are significantly higher than against
M. tb
and
M. bovis
BCG.
1338780-86-1
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-101867 | 1338780-86-1
AU1235 | 1338780-86-1 | 2mg | 1100元 |
| 2024/04/30 | HY-101867 | 1338780-86-1
AU1235 | 1338780-86-1 | 5mg | 1800元 |
1338780-86-1, 1338780-86-1 相关搜索:
- 药靶配体
- 细胞生物学试剂
- 化合物AU1235
- 结核分枝杆菌金刚烷脲尿素抑制剂(AU1235)
- 1338780-86-1
- Inhibitor,MmpL3,transport,tuberculosis,AU1235,cell,AU 1235,AU-1235,synthesis,inhibit,Bacterial,wall,Mycobacterium
- Urea, N-tricyclo[3.3.1.13,7]dec-1-yl-N'-(2,3,4-trifluorophenyl)-
- AU1235;AU-1235;AU 1235
- AU1235