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142873-41-4

142873-41-4, 142873-41-4, 结构式
142873-41-4
CAS号:
142873-41-4
英文名:
5-Benzofuranamine, 2,3-dihydro-2,4,6,7-tetramethyl-2-[(4-phenyl-1-piperidinyl)methyl]-
英文别名:
Lipid peroxidation inhibitor 1;5-Benzofuranamine, 2,3-dihydro-2,4,6,7-tetramethyl-2-[(4-phenyl-1-piperidinyl)methyl]-
中文名:
142873-41-4
中文别名:
脂质过氧化抑制剂1;化合物 T10166
CBNumber:
CB83339590
分子式:
C24H32N2O
分子量:
364.52368
MOL File:
142873-41-4.mol

142873-41-4化学性质

沸点:
520.4±50.0 °C(Predicted)
密度:
1.090±0.06 g/cm3(Predicted)
储存条件:
Store at -20°C
溶解度:
Soluble in DMSO
酸度系数(pKa):
8.09±0.10(Predicted)
安全信息

142873-41-4性质、用途与生产工艺

生物活性

Lipid peroxidation inhibitor 1 是一种脂质过氧化 (lipid peroxidation) 抑制剂,其 IC50 值为 0.07 μM。

靶点

IC50: 0.07μM (lipid peroxidation)

体外研究

Among the compounds synthesized, Lipid peroxidation inhibitor 1 (26n) exhibits potent effects in the inhibition of lipid peroxidation, with an IC 50 of 0.07 μM.

体内研究

Basic molecules 8a and 27 exhibit significant effects against (methamphetamine) MAP-induced hypermotility. Except in these compounds, a phenyl group adjacent to the methyl group in position 2 at a distance seems to be indispensable (compare compounds 26m, o, p with compounds Lipid peroxidation inhibitor 1 (26n), q, r). Among these compounds, Lipid peroxidation inhibitor 1 which has a phenylpiperidinyl group in position 2 is found to be most effective.

142873-41-4 上下游产品信息

上游原料

下游产品


142873-41-4 生产厂家

全球有 7家供应商   142873-41-4国内生产厂家
供应商联系电话电子邮件国家产品数优势度
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com 美国 14059 65
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn 美国 4863 58
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 marketing@targetmol.com 美国 19892 58
天津普西唐生物医药科技有限公司 010-60605840 psaitong@jm-bio.com 中国 29778 58
TargetMol中国(陶术生物) 4008200310 marketing@tsbiochem.com 中国 24018 58
南通菡芳生物科技有限公司 3674309880 hanfangpharma@126.com 中国 30968 58
 

142873-41-4, 142873-41-4 相关搜索:

  • 化合物 T10166
  • 脂质过氧化抑制剂1
  • 142873-41-4
  • Lipid peroxidation inhibitor 1
  • 5-Benzofuranamine, 2,3-dihydro-2,4,6,7-tetramethyl-2-[(4-phenyl-1-piperidinyl)methyl]-
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