108237-91-8
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- CAS号:
- 108237-91-8
- 英文名:
- 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
- 英文别名:
- RCGD423;RCGD 432;N-(4-Bromophenyl)-4-phenylthiazol-2-amine;2-Thiazolamine, N-(4-bromophenyl)-4-phenyl-;4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine;Regulator of cartilage growth and differentiation (RCGD) 423;RCGD423,inhibit,RCGD 423,Inhibitor,Interleukin Related,RCGD-423
- 中文名:
- 108237-91-8
- 中文别名:
- 化合物RCGD423;RCGD 423,GP130调制器;N-(4-溴苯基)-4-苯基噻唑-2-胺
- CBNumber:
- CB94664083
- 分子式:
- C15H11BrN2S
- 分子量:
- 331.23
- MOL File:
- 108237-91-8.mol
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108237-91-8化学性质
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储存条件:
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under inert gas (nitrogen or Argon) at 2–8 °C
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溶解度:
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DMSO:34.0(Max Conc. mg/mL);102.6(Max Conc. mM)
Ethanol:34.0(Max Conc. mg/mL);102.6(Max Conc. mM)-
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形态:
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A solid
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108237-91-8性质、用途与生产工艺
RCGD-423 是 Glycoprotein 130 (gp130, IL6ST, IL6-beta, CD130) 信号调节剂，可调节软骨生长和分化。
RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair.
RCGD423 greatly reduces chondrocyte hypertrophy, loss and degeneration while increasing chondrocyte proliferation beyond that observed in response to injury in a rat partial meniscectomy model. Moreover, RCGD 423 improves cartilage healing in a rat full-thickness osteochondral defect model, increasing proliferation of mesenchymal cells in the defect and also inhibiting breakdown of cartilage matrix in de novo generated cartilage.
108237-91-8
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-114775 | 108237-91-8
RCGD423 | 108237-91-8 | 10mM * 1mLin DMSO | 792元 |
| 2024/04/30 | S6579 | 108237-91-8
RCGD423 | 108237-91-8 | 5mg | 795.42元 |
108237-91-8, 108237-91-8 相关搜索:
- 药靶配体
- RCGD 423,GP130调制器
- 化合物RCGD423
- N-(4-溴苯基)-4-苯基噻唑-2-胺
- 108237-91-8
- Regulator of cartilage growth and differentiation (RCGD) 423
- RCGD423,inhibit,RCGD 423,Inhibitor,Interleukin Related,RCGD-423
- N-(4-Bromophenyl)-4-phenylthiazol-2-amine
- RCGD 432
- 2-Thiazolamine, N-(4-bromophenyl)-4-phenyl-
- RCGD423
- 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine