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Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-

Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- structure

CAS No.: 333314-79-7

Chemical Name:: Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-

Synonyms: HIF1-IN-3;WAY-311318;N-((8-hydroxyquinolin-7-yl)(4-methoxyphenyl)methyl)-3-phenylpropanamide;Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-;Hypoxia-inducible factors,HIF1 IN 3?,Inhibitor,HIFs,inhibit,HIF-PH,HIF1IN3?,Anticancer,HIF/HIF Prolyl-Hydroxylase

CBNumber:: CB010911840

Molecular Formula:: C26H24N2O3

Molecular Weight:: 412.48

MDL Number:

MOL File:: 333314-79-7.mol

Last updated:2023-05-21 10:59:17

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Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- Properties

Boiling point	698.1±55.0 °C(Predicted)
Density	1.229±0.06 g/cm3(Predicted)
storage temp.	4°C, protect from light
solubility	DMSO : 125 mg/mL (303.04 mM; Need ultrasonic)
pka	4.31±0.50(Predicted)

Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- Chemical Properties,Uses,Production

Biological Activity

HIF1-IN-3 (compound F4) is a potent HIF1 inhibitor with an EC50 value of 0.9 μM. HIF1-IN-3 can be used for researching anticancer[1].

References

[1]. Poloznikov AA, et al. Structure-activity relationship for branched oxyquinoline HIF activators: Effect of modifications to phenylacetamide "tail". Biochimie. 2017;133:74-79.

Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- Suppliers

Global( 11)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Han Sheng New Material Technology Co.，Ltd	+8617798174412	admin01@hsnm.com.cn	China	2118	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9747	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973 13515979683	sales@jamxmpharmatech.com	China	1079	58
Hefei Mokai Pharmaceutical Technology Co., Ltd	18130062233	3362556465@qq.com	China	8000	58
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	61720	58
Xi'an Kaixin Biotechnology Co., Ltd	029-68881181 13619217766	3495811982@qq.com	China	2756	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24024	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	market@aladdin-e.com	China	48518	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Wuhan Han Sheng New Material Technology Co.，Ltd	58
Aladdin Scientific	58
Shanghai Chaolan Chemical Technology Center	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58
Hefei Mokai Pharmaceutical Technology Co., Ltd	58
Bide Pharmatech Ltd.	58
Xi'an Kaixin Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58

Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- N-((8-hydroxyquinolin-7-yl)(4-methoxyphenyl)methyl)-3-phenylpropanamide HIF1-IN-3 Hypoxia-inducible factors,HIF1 IN 3?,Inhibitor,HIFs,inhibit,HIF-PH,HIF1IN3?,Anticancer,HIF/HIF Prolyl-Hydroxylase WAY-311318 333314-79-7