ChemicalBook >> CAS DataBase List >>15-Lipoxygenase Inhibitor 1
15-Lipoxygenase Inhibitor 1
- CAS No.
- 928853-86-5
- Chemical Name:
- 15-Lipoxygenase Inhibitor 1
- Synonyms
- 4-MMPB;15-Lipoxygenast Inhibitorl;15-Lipoxygenase Inhibitor I;15-Lipoxygenase Inhibitor 1;15-Lipoxygenase Inhibitor 1(4-MMPB);15-Lipoxygenase Inhibitor 1 Exclusive;4-methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine;5H-Pyrimido[4,5-b][1,4]benzothiazine, 4-methyl-2-(4-methyl-1-piperazinyl)-;LOX,4 MMPB,radical,Inhibitor,inhibit,4-MMPB,scavenging,Lipoxygenase,cancer,Apoptosis,4MMPB,inhibition
- CBNumber:
- CB02589916
- Molecular Formula:
- C16H19N5S
- Molecular Weight:
- 313.42
- MDL Number:
- MOL File:
- 928853-86-5.mol
Last updated:2023-05-21 10:59:17
15-Lipoxygenase Inhibitor 1 price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10010468 | 15-Lipoxygenase Inhibitor 1 ≥95% | 928853-86-5 | 500μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 10010468 | 15-Lipoxygenase Inhibitor 1 ≥95% | 928853-86-5 | 1mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 10010468 | 15-Lipoxygenase Inhibitor 1 ≥95% | 928853-86-5 | 5mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 10010468 | 15-Lipoxygenase Inhibitor 1 ≥95% | 928853-86-5 | 10mg | $426 | 2024-03-01 | Buy |
| ChemScene | CS-0066087 | 4-MMPB 98.31% | 928853-86-5 | 10mg | $450 | 2021-12-16 | Buy |
15-Lipoxygenase Inhibitor 1 Chemical Properties,Uses,Production
Biological Activity
4-MMPB is a selective lipoxygenase 15-lipoxygenase inhibitor with IC50 value of 18 μM. The IC50 values of it against soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1) were 19.5 μM and 19.1 μM, respectively. It has potential for prostate cancer research.
in vitro
4-MMPB has an IC 50 of 69.6 μM for DPPH bleaching.
4-MMPB exhibits cytotoxic activity on human PC-3 and HFF3 cell lines.
4-MMPB (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells.
Cell Viability Assay
| Cell Line: | DU145 cells, PC-3 cells, HFF3 cells |
| Concentration: | 9.57 μM, 19.94 μM, 39.88 μM, 79.77 μM, 159.53 μM |
| Incubation Time: | 24 hours, 48 hours, 72 hours |
| Result: | IC 50 s of 79.76 μM (24 hours), 51.05 μM (48 hours) and 41.48 μM (72 hours) for PC-3 cells, and 255.25 μM (24 hours), 130.81 μM (48 hours) and 98.91 μM (72 hours) for HFF3 cells. |
target
IC50: 18 μM (15-lipoxygenase)
15-Lipoxygenase Inhibitor 1 Preparation Products And Raw materials
Raw materials
Preparation Products
15-Lipoxygenase Inhibitor 1 Suppliers
Global( 26)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9767 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Luofa Biochemical Technology Co., Ltd. | 021-51111890 15317326293 | sales@molnova.com | China | 4196 | 58 |
928853-86-5(15-Lipoxygenase Inhibitor 1)Related Search:
15-Lipoxygenase Inhibitor 1
15-Lipoxygenase Inhibitor I
15-Lipoxygenase Inhibitor 1 Exclusive
4-methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine
15-Lipoxygenase Inhibitor 1(4-MMPB)
4-MMPB
15-Lipoxygenast Inhibitorl
LOX,4 MMPB,radical,Inhibitor,inhibit,4-MMPB,scavenging,Lipoxygenase,cancer,Apoptosis,4MMPB,inhibition
5H-Pyrimido[4,5-b][1,4]benzothiazine, 4-methyl-2-(4-methyl-1-piperazinyl)-
928853-86-5