ChemicalBook >> CAS DataBase List >>OTS964
OTS964
- CAS No.
- 1338545-07-5
- Chemical Name:
- OTS964
- Synonyms
- OTS964;CS-2531;OTS964 HCl;OTS964; OTS 964;OTS964+OTS964 HCl;OTS964 HYDROCHLORIDE;(R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one;(R)-9-[4-[1-(Dimethylamino)propan-2-yl]phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one Hydrochloride
- CBNumber:
- CB02737339
- Molecular Formula:
- C23H24N2O2S
- Molecular Weight:
- 392.51386
- MDL Number:
- MFCD28386220
- MOL File:
- 1338545-07-5.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2934999090 |
OTS964 price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17052 | OTS964 (hydrochloride) | 1338545-07-5 | 1mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 17052 | OTS964 (hydrochloride) | 1338545-07-5 | 5mg | $168 | 2024-03-01 | Buy |
| Cayman Chemical | 17052 | OTS964 (hydrochloride) | 1338545-07-5 | 500μg | $49 | 2024-03-01 | Buy |
| TRC | O712970 | OTS964 | 1338545-07-5 | 25mg | $1175 | 2021-12-16 | Buy |
| TRC | O712970 | OTS964 | 1338545-07-5 | 10mg | $590 | 2021-12-16 | Buy |
OTS964 Chemical Properties,Uses,Production
Description
OTS964 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK; IC50 = 28 nM). It specifically blocks cytokinesis, leading to apoptosis, in a broad range of cancer cells. OTS964 induces apoptosis of human lung cancer cells in mouse xenografts.
Uses
OTS 964 works through cytokinesis and is an effective TOPK inhibitor which has been shown to cause tumor suppression in xenografts of human cancer.
References
1. matsuo y, park jh2, miyamoto t, et al. topk inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis. ci transl med. 2014 oct 22;6(259):259ra145.
OTS964 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 95)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hebei Duling International Trade Co. LTD | +8618712993135 | sales01@hbduling.cn | China | 15734 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
1338545-07-5(OTS964)Related Search:
OTS964
(R)-9-[4-[1-(Dimethylamino)propan-2-yl]phenyl]-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one Hydrochloride
(R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
OTS964 HYDROCHLORIDE
OTS964; OTS 964
CS-2531
OTS964 HCl
OTS964+OTS964 HCl
1338545-07-5
C23H24N2O2SHCl
API