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7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin

7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Structure
7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin structure
CAS No.
1428730-05-5
Chemical Name:
7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin
Synonyms
NeuroSensor 521;NeuroSensor 521 >=98% (HPLC);7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin;7-(Diethylamino)-4-(4-methoxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxaldehyde;2H-1-Benzopyran-3-carboxaldehyde, 7-(diethylamino)-4-(4-methoxyphenyl)-2-oxo-
CBNumber:
CB02750699
Molecular Formula:
C21H21NO4
Molecular Weight:
351.4
MDL Number:
MOL File:
1428730-05-5.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
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7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Properties

Boiling point 557.2±50.0 °C(Predicted)
Density 1.260±0.06 g/cm3(Predicted)
storage temp. -70°C
solubility DMSO: soluble10mg/mL, clear
pka 2.78±0.20(Predicted)
form powder
color yellow to orange

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3

7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0871 NeuroSensor 521 ≥98% (HPLC) 1428730-05-5 25mg $644 2022-05-15 Buy
TRC N391018 NeuroSensor 521 1428730-05-5 1mg $155 2021-12-16 Buy
Product number Packaging Price Buy
SML0871 25mg $644 Buy
N391018 1mg $155 Buy

7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Chemical Properties,Uses,Production

Uses

Neurosensor 521 is a selective noradrenalin and dopamine fluorescent indicator.

Biochem/physiol Actions

NeuroSensor 521 is a fluorescent turn-on sensor designed for the selective visualization of norepinephrine over epinephrine in fixed and live cells and the fluorescence is not affected by fixation. NeuroSensor 521 binds to all primary amines, but binds catecholamines such as dopamine and norepinephrine more tightly than other biogenic amines such as glutamate and does not interact with secondary amines such as epinephrine. Because of the spectral properties of NeuroSensor 521, the unbound and bound states can be monitored using 440 and 488 nm excitation, respectively. In chromaffin cells NeuroSensor 521 stained the norepinephrine-containing cells preferentially over epinephrine-containing cells under identical conditions.

7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Preparation Products And Raw materials

Raw materials

Preparation Products

7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Sigma-Aldrich 80
Shanghai EFE Biological Technology Co., Ltd. 58
Energy Chemical 58
Changzhou Furuisi Biotechnology Co., Ltd 58
7-Diethylamino-3-formyl-4-(4’-methoxyphenyl)coumarin NeuroSensor 521 7-(Diethylamino)-4-(4-methoxyphenyl)-2-oxo-2H-1-benzopyran-3-carboxaldehyde NeuroSensor 521 >=98% (HPLC) 2H-1-Benzopyran-3-carboxaldehyde, 7-(diethylamino)-4-(4-methoxyphenyl)-2-oxo- 1428730-05-5