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Erlotinib D6 HCl

Erlotinib D6 HCl Structure
Erlotinib D6 HCl structure
CAS No.
1189953-78-3
Chemical Name:
Erlotinib D6 HCl
Synonyms
Erlotinib D6;OSI-774 D6 hydrochloride;Erlotiniβ-d6 Hydrochloride;CP-358774 D6 hydrochloride;NSC 718781 D6 hydrochloride;[2H6]-Erlotinib Hydrochloride;Erlotinib Hydrochloride Impurity G
CBNumber:
CB03049808
Molecular Formula:
C22H18ClD6N3O4
Molecular Weight:
435.933630668
MDL Number:
MFCD09840535
MOL File:
1189953-78-3.mol
MSDS File:
SDS
Last updated:2023-06-08 09:03:09
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Erlotinib D6 HCl Properties

storage temp. Store at -20°C
solubility DMSO: slightly, heated,Methanol: slightly soluble
form A solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

Erlotinib D6 HCl price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22101 Erlotinib-d6 (hydrochloride) ≥99% deuterated forms (d1-d6) 1189953-78-3 1mg $279 2024-03-01 Buy
TRC E625002 Erlotinib-d6Hydrochloride 1189953-78-3 1mg $145 2021-12-16 Buy
AK Scientific 7728DG ErlotinibD6Hydrochloride 1189953-78-3 1mg $409 2021-12-16 Buy
American Custom Chemicals Corporation RDL0006809 ERLOTINIB-D6-HYDROCHLORIDE 95.00% 1189953-78-3 10MG $1871.1 2021-12-16 Buy
Product number Packaging Price Buy
22101 1mg $279 Buy
E625002 1mg $145 Buy
7728DG 1mg $409 Buy
RDL0006809 10MG $1871.1 Buy

Erlotinib D6 HCl Chemical Properties,Uses,Production

Description

Erlotinib-d6 (hydrochloride) contains six deuterium atoms located on the methoxy group. It is intended for use as an internal standard for the quantification of erlotinib by GC- or LC-MS. Erlotinib is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. Formulations containing erlotinib are used to treat certain forms of cancer, including non-small cell lung cancer.

Uses

Erlotinib D6 HCl is a Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, Antineoplastic.;Labeled Erlotinib, intended for use as an internal standard for the quantification of Erlotinib by GC- or LC-mass spectrometry.

Erlotinib D6 HCl Preparation Products And Raw materials

Raw materials

Preparation Products

Erlotinib D6 HCl Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
SIMSON PHARMA LIMITED 		+91-8291074273 k.das@simsonpharma.com India 228 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 6854 65
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17981 56
Artis Biotech Co. Ltd. 19138486554 18582380095 sales@artisbio.com China 3015 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Standardpharm Co. Ltd. 		58
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
SIMSON PHARMA LIMITED 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Daicel Chiral Technologies (China)CO.,LTD 65
ChemStrong Scientific Co.,Ltd 56
Artis Biotech Co. Ltd. 58

View Lastest Price from Erlotinib D6 HCl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Erlotinib-D6 Hydrochloride pictures 2023-05-27 Erlotinib-D6 Hydrochloride
1189953-78-3
 US $0.00-0.00 / mg 1mg 96% 50 mg Simson Pharma limited

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Erlotinib D6 Erlotinib Hydrochloride Impurity G [2H6]-Erlotinib Hydrochloride CP-358774 D6 hydrochloride NSC 718781 D6 hydrochloride OSI-774 D6 hydrochloride Erlotiniβ-d6 Hydrochloride 1189953-78-3