ChemicalBook >> CAS DataBase List >>UCM05

UCM05

CAS No.
1094451-90-7
Chemical Name:
UCM05
Synonyms
UCM05;G 28UCM;UCM05(G 28UCM);Benzoic acid, 3,4,5-trihydroxy-, 1,1'-(1,3-naphthalenediyl) ester;3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate
CBNumber:
CB03067587
Molecular Formula:
C24H16O10
Molecular Weight:
464.38
MDL Number:
MOL File:
1094451-90-7.mol
Last updated:2023-07-14 17:31:58

UCM05 Properties

Boiling point 895.1±65.0 °C(Predicted)
Density 1.652±0.06 g/cm3(Predicted)
solubility DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:40): 0.02 mg/ml
form A crystalline solid
pka 7.50±0.25(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

UCM05 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19090 UCM05 ≥95% 1094451-90-7 1mg $32 2024-03-01 Buy
Cayman Chemical 19090 UCM05 ≥95% 1094451-90-7 5mg $116 2024-03-01 Buy
Cayman Chemical 19090 UCM05 ≥95% 1094451-90-7 10mg $214 2024-03-01 Buy
Tocris 5446 G28UCM ≥98%(HPLC) 1094451-90-7 50 $883 2021-12-16 Buy
Tocris 5446 G28UCM ≥98%(HPLC) 1094451-90-7 10 $210 2021-12-16 Buy
Product number Packaging Price Buy
19090 1mg $32 Buy
19090 5mg $116 Buy
19090 10mg $214 Buy
5446 50 $883 Buy
5446 10 $210 Buy

UCM05 Chemical Properties,Uses,Production

Uses

G 28UCM is a fatty acid synthase inhibitor with anticancer activity, novel inhibitor of fatty acid synthase with anticancer activity.

Uses

UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 μM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of HER2, Akt, and ERK1/2, and growth of established xenografts in vivo. UCM05 also blocks the GTP-binding site of the cell division protein FtsZ from Bacillus, preventing bacterial division.[Cayman Chemical]

storage

Store at -20°C

132-86-5
1094451-90-7
Synthesis of UCM05 from 1,3-DIHYDROXYNAPHTHALENE

UCM05 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3500 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131980 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
BOC Sciences -- info@bocsci.com USA 0 65
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
UCM05 G 28UCM 3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate Benzoic acid, 3,4,5-trihydroxy-, 1,1'-(1,3-naphthalenediyl) ester UCM05(G 28UCM) 1094451-90-7