ChemicalBook >> CAS DataBase List >>PBTZ169
PBTZ169
- CAS No.
- 1377239-83-2
- Chemical Name:
- PBTZ169
- Synonyms
- CS-2309;Macozinone;PBTZ169 (PBTZ 169;PBTZ169;PBTZ-169;PBTZ 169;2-(4-(Cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-trifluoromethyl-4H-1,3-benzothiazin-4-one; 2-[4-(Cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one;4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-;2-(4-(Cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one
- CBNumber:
- CB03128778
- Molecular Formula:
- C20H23F3N4O3S
- Molecular Weight:
- 456.48
- MDL Number:
- MOL File:
- 1377239-83-2.mol
Last updated:2023-06-08 09:02:51
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO:4.6(Max Conc. mg/mL);10.1(Max Conc. mM) |
| form | A crystalline solid |
| FDA UNII | A3M1353L40 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| NFPA 704 |
|
PBTZ169 price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22202 | PBTZ169 ≥98% | 1377239-83-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 22202 | PBTZ169 ≥98% | 1377239-83-2 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 22202 | PBTZ169 ≥98% | 1377239-83-2 | 10mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 22202 | PBTZ169 ≥98% | 1377239-83-2 | 25mg | $533 | 2024-03-01 | Buy |
| TRC | P216563 | PBTZ169 | 1377239-83-2 | 5mg | $140 | 2021-12-16 | Buy |
PBTZ169 Chemical Properties,Uses,Production
Description
PBTZ169 is an antibiotic with antimycobacterial activity. It is an irreversible inhibitor of DprE1, an essential enzyme for cell wall synthesis in mycobacteria. PBTZ169 is active against M. tuberculosis in vitro (MIC = ≤0.19 ng/ml) without inducing cytotoxicity in Vero cells when used at concentrations up to 125 μM. It reduces the bacterial burden in the lung and spleen in a mouse model of chronic tuberculosis when administered at a dose of 50 mg/kg per day.
Uses
PBTZ169 is a potent irreversible inhibitor of decaprenylphosphoryl-beta-D-ribose 2-epimerase (DprE1), and display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.
PBTZ169 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 57)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 |
View Lastest Price from PBTZ169 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![2-[4-(Cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/2cf3e946-85d4-4e71-b719-f327237e68f0.png) |
2020-01-02 | 2-[4-(Cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one
1377239-83-2
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
-
- 2-[4-(Cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one
1377239-83-2
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co
2-(4-(Cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-trifluoromethyl-4H-1,3-benzothiazin-4-one
Macozinone
PBTZ169;PBTZ-169;PBTZ 169
CS-2309
PBTZ169 (PBTZ 169
2-[4-(Cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one
4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-
2-(4-(Cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one
1377239-83-2