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BMS-955829

BMS-955829 structure

CAS No.: 1375751-08-8

Chemical Name:: BMS-955829

Synonyms: BMS-955829;(4R,5R)-5-(2,5-DIFLUOROPHENYL)-4-(5-(PHENYLETHYNYL)PYRIDIN-3-YL)OXAZOLIDIN-2-ONE;2-Oxazolidinone, 5-(2,5-difluorophenyl)-4-[5-(2-phenylethynyl)-3-pyridinyl]-, (4R,5R)-

CBNumber:: CB03344769

Molecular Formula:: C22H14F2N2O2

Molecular Weight:: 376.36

MDL Number:: MFCD30471079

MOL File:: 1375751-08-8.mol

Last updated:2023-03-31 09:12:58

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BMS-955829 Properties

Boiling point	589.2±50.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
pka	10.38±0.60(Predicted)

BMS-955829 Chemical Properties,Uses,Production

Description

BMS-955829 is a Positive allosteric modulators (PAMs). BMS-955829 shows high functional PAM potency, excellent mGluR5 binding affinity, low glutamate fold shift, and high selectivity for the mGluR5 subtype. BMS-955829 is a potent mGluR5 PAM (EC50 = 2.6 ± 1.0 nM; n = 6), devoid of inherent mGluR5 agonist activity (EC50 > 30μM). The measured binding Ki of BMS-955829 was found to be 1.6 nM, which was in good agreement with its functional potency.

BMS-955829 Preparation Products And Raw materials

Raw materials

Preparation Products

BMS-955829 Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

BMS-955829 (4R,5R)-5-(2,5-DIFLUOROPHENYL)-4-(5-(PHENYLETHYNYL)PYRIDIN-3-YL)OXAZOLIDIN-2-ONE 2-Oxazolidinone, 5-(2,5-difluorophenyl)-4-[5-(2-phenylethynyl)-3-pyridinyl]-, (4R,5R)- 1375751-08-8