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N-Boc-PEG4-bromide

N-Boc-PEG4-bromide Structure
N-Boc-PEG4-bromide structure
CAS No.
1392499-32-9
Chemical Name:
N-Boc-PEG4-bromide
Synonyms
BocNH-PEG4-Br;Br-PEG4-NHBoc;N-Boc-PEG4-bromide;N-Boc-PEG5-bromide;BocNH-PEG4-CH2CH2Br;N-Boc-PEG4-bromide N-Boc-;tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate;tert-butyl N-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate;5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-bromo-, 1,1-dimethylethyl ester;ADC,antibody-drug,PROTAC Linkers,ADC Linkers,N-Boc-PEG-5-bromide,cleavable,inhibit,conjugates,Inhibitor,N Boc PEG5 bromide,NBocPEG5bromide,Antibody-drug conjugates linkers
CBNumber:
CB03373736
Molecular Formula:
C15H30BrNO6
Molecular Weight:
400.31
MDL Number:
MFCD31536756
MOL File:
1392499-32-9.mol
Last updated:2024-03-25 11:48:53
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N-Boc-PEG4-bromide Properties

Boiling point 459.3±40.0 °C(Predicted)
Density 1.223±0.06 g/cm3(Predicted)
solubility Soluble in DCM
pka 12.23±0.46(Predicted)

N-Boc-PEG4-bromide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23789 N-Boc-PEG4-bromide 98% 1392499-32-9 250mg $540 2021-12-16 Buy
Activate Scientific AS103627 BocNH-PEG4-CH2CH2Br 95+% 1392499-32-9 1g $665 2021-12-16 Buy
AK Scientific 0954EB N-Boc-PEG5-bromide 1392499-32-9 1g $856 2021-12-16 Buy
Crysdot CD64000172 N-BOc-peg4-bromide 95% 1392499-32-9 1g $600 2021-12-16 Buy
Acrotein AC-8220 BocNH-PEG4-CH2CH2Br 97% 1392499-32-9 0.25g $220 2021-12-16 Buy
Product number Packaging Price Buy
BP-23789 250mg $540 Buy
AS103627 1g $665 Buy
0954EB 1g $856 Buy
CD64000172 1g $600 Buy
AC-8220 0.25g $220 Buy

N-Boc-PEG4-bromide Chemical Properties,Uses,Production

Description

N-Boc-PEG4-bromide is a PEG linker containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Biological Activity

N-Boc-PEG5-bromide is a PROTAC linker that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

N-Boc-PEG4-bromide Preparation Products And Raw materials

Raw materials

Preparation Products

N-Boc-PEG4-bromide Suppliers

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Borenpharm Co., Ltd 		027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 6859 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501 product@acmec-e.com China 33350 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Supplier Advantage
Accela ChemBio Inc. 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
TargetMol Chemicals Inc. 		58
Wuhan Borenpharm Co., Ltd 		58
Shanghai UCHEM Inc. 		58
Hangzhou Huarong Pharm Co., Ltd. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58

View Lastest Price from N-Boc-PEG4-bromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Br-PEG4-NHBoc pictures 2024-03-25 Br-PEG4-NHBoc
1392499-32-9
 US $0.00 / g 5g >98.00% 5g Xian confluore Biological Technology Co., Ltd.
  • Br-PEG4-NHBoc pictures
  • Br-PEG4-NHBoc
    1392499-32-9
  • US $0.00 / g
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.

1392499-32-9(N-Boc-PEG4-bromide)Related Search:

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2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol t-Boc-N-amido-PEG5-acid O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) N-Boc-PEG5-alcohol Biotin-PEG36-PFP ester
N-(Amino-PEG3)-N-bis(PEG4-Boc) BocNH-PEG5-acid Biotin-PEG6-t-butyl ester FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID 2-[2-[2-T-BOC-AMINOETHOXY]ETHOXY]ETHYL BROMIDE
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1of4

N-Boc-PEG4-bromide BocNH-PEG4-CH2CH2Br N-Boc-PEG5-bromide Br-PEG4-NHBoc 5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-bromo-, 1,1-dimethylethyl ester tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate ADC,antibody-drug,PROTAC Linkers,ADC Linkers,N-Boc-PEG-5-bromide,cleavable,inhibit,conjugates,Inhibitor,N Boc PEG5 bromide,NBocPEG5bromide,Antibody-drug conjugates linkers tert-butyl N-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate N-Boc-PEG4-bromide N-Boc- BocNH-PEG4-Br 1392499-32-9 C15H30BrNO6