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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride structure

CAS No.: 1620278-72-9

Chemical Name:: 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

Synonyms: TLR7/8 agonist-5d;TLR7/8 agonist 1 2HCl;8 agonist 1 dihydrochloride;TLR7/8 Agonist 1 (hydrochloride);TLR7/8 Agonist 5d (hydrochloride);TLR7/8 agonist 1 (dihydrochloride);1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride;Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit

CBNumber:: CB03374339

Molecular Formula:: C22H26ClN5

Molecular Weight:: 395.94

MDL Number:: MFCD31657341

MOL File:: 1620278-72-9.mol

Last updated:2023-05-21 10:59:17

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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Properties

storage temp.	Store at -20°C
solubility	DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
form	A solid

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	28451	TLR7/8 Agonist 1 (hydrochloride)	1620278-72-9	500μg	$73	2024-03-01	Buy
Cayman Chemical	28451	TLR7/8 Agonist 1 (hydrochloride)	1620278-72-9	5mg	$468	2024-03-01	Buy
Cayman Chemical	28451	TLR7/8 Agonist 1 (hydrochloride)	1620278-72-9	1mg	$131	2024-03-01	Buy
AK Scientific	3353EB	TLR7/8agonist1(dihydrochloride)	1620278-72-9	1mg	$243	2021-12-16	Buy
ChemScene	CS-0032947	TLR7/8agonist1(dihydrochloride) 98.47%	1620278-72-9	10mg	$550	2021-12-16	Buy

Product number	Packaging	Price	Buy
28451	500μg	$73	Buy
28451	5mg	$468	Buy
28451	1mg	$131	Buy
3353EB	1mg	$243	Buy
CS-0032947	10mg	$550	Buy

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Chemical Properties,Uses,Production

Biological Activity

TLR7/8 agonist 1 dihydrochloride is a dual agonist of the toll-like receptor TLR7/TLR8.

in vitro

TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity.It retains TLR7- agonistic activity with an EC ₅₀ of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.

target

TLR7/TLR8

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Suppliers

Global( 50)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Henan Alfa Chemical Co., Ltd	+8618339805032	alfa4@alfachem.cn	China	12975	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Nanjing Qishi Biotechnology Co. Ltd.	19822610310	3122922726@qq.com	China	1346	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4153	55

Supplier	Advantage
BOC Sciences	58
Career Henan Chemica Co	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Henan Alfa Chemical Co., Ltd	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Nanjing Qishi Biotechnology Co. Ltd.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride TLR7/8 agonist 1 (dihydrochloride) TLR7/8 agonist-5d TLR7/8 Agonist 1 (hydrochloride) 8 agonist 1 dihydrochloride TLR7/8 Agonist 5d (hydrochloride) Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit TLR7/8 agonist 1 2HCl 1620278-72-9