ChemicalBook >> CAS DataBase List >>2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid structure

CAS No.: 1210360-87-4

Chemical Name:: 2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid

Synonyms: CAY10781;2-(6-oxo-2-pyridin-3-yl-1H-pyrimidin-5-yl)acetic acid;6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]acetic acid;5-Pyrimidineacetic acid, 3,4-dihydro-4-oxo-2-(3-pyridinyl)-;2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid

CBNumber:: CB03988596

Molecular Formula:: C11H9N3O3

Molecular Weight:: 231.21

MDL Number:: MFCD17430309

MOL File:: 1210360-87-4.mol

Last updated:2023-09-04 15:50:00

Request For Quotation

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Properties

storage temp.	-20°C
solubility	DMF: insol,DMSO: 10 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form	A solid

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	500mg	$529	2021-12-16	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	1g	$857	2021-12-16	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	5g	$2057	2021-12-16	Buy
aablocks	AA00JB5Y	[6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]aceticacid	1210360-87-4	10g	$3248	2021-12-16	Buy

Product number	Packaging	Price	Buy
AA00JB5Y	500mg	$529	Buy
AA00JB5Y	1g	$857	Buy
AA00JB5Y	5g	$2057	Buy
AA00JB5Y	10g	$3248	Buy

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Chemical Properties,Uses,Production

Biological Activity

CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1 It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.

References

1.Perez-Miller, S., Patek, M., Moutal, A., et al.In silico identification and validation of inhibitors of the interaction between neuropilin receptor 1 and SARS-CoV-2 Spike proteinbioRxiv308783(2020)

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Shanghai EFE Biological Technology Co., Ltd.	58
DC Chemicals	58
TargetMol Chemicals Inc.	58

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid Spectrum

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid(1210360-87-4)¹HNMR

2-(6-oxo-2-(pyridin-3-yl)-1,6-dihydropyrimidin-5-yl)acetic acid 5-Pyrimidineacetic acid, 3,4-dihydro-4-oxo-2-(3-pyridinyl)- CAY10781 6-Oxo-2-(3-pyridinyl)-1,6-dihydro-5-pyrimidinyl]acetic acid 2-(6-oxo-2-pyridin-3-yl-1H-pyrimidin-5-yl)acetic acid 1210360-87-4