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THPP-1

THPP-1 structure

CAS No.: 1257051-63-0

Chemical Name:: THPP-1

Synonyms: THPP-1;PDE10A,SIMA,object,THPP 1,recognition,Phosphodiesterase (PDE),Inhibitor,inhibit,novel,THPP-1,THPP1;Methanone, [2-(6-chloro-3-pyridinyl)-7,8-dihydro-4-(2-methoxyethoxy)pyrido[4,3-d]pyrimidin-6(5H)-yl]imidazo[1,5-a]pyridin-1-yl-

CBNumber:: CB06127943

Molecular Formula:: C23H21ClN6O3

Molecular Weight:: 464.9

MDL Number:

MOL File:: 1257051-63-0.mol

Last updated:2023-05-21 10:59:17

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THPP-1 Properties

Density	1.45±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: 31.25 mg/mL (67.22 mM)
form	A solid
pka	4.70±0.30(Predicted)

THPP-1 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0066613	THPP-1 98.95%	1257051-63-0	5mg	$450	2021-12-16	Buy
ChemScene	CS-0066613	THPP-1 98.95%	1257051-63-0	10mg	$750	2021-12-16	Buy
ChemScene	CS-0066613	THPP-1 98.95%	1257051-63-0	50mg	$2250	2021-12-16	Buy
ChemScene	CS-0066613	THPP-1 98.95%	1257051-63-0	100mg	$3350	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0066613	5mg	$450	Buy
CS-0066613	10mg	$750	Buy
CS-0066613	50mg	$2250	Buy
CS-0066613	100mg	$3350	Buy

THPP-1 Chemical Properties,Uses,Production

Biological Activity

THPP-1, a chemical probe recommended by SGC, is a potent and orally active inhibitor of phosphodiesterase 10A (PDE10A) with Ki values of 1 nM and 1.3 nM for human and rat, respectively. THPP-1 has good pharmacological properties.

target

IC50: 1-1.3 nM (PDE10A).

THPP-1 Preparation Products And Raw materials

Raw materials

Preparation Products

THPP-1 Suppliers

Global( 20)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4153	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	27322	60
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9767	58
Shanghai Dongyang Biotechnology Co., Ltd.	0512-0512-13601744364 13601744364	chemsharker@126.com	China	879	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	021-51816796-820 13611835272	sales2@sunwaypharm.com	China	44487	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	29778	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
InvivoChem	58
TargetMol Chemicals Inc.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai Chaolan Chemical Technology Center	58
Shanghai Dongyang Biotechnology Co., Ltd.	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	58
Beijing Jin Ming Biotechnology Co., Ltd.	58

THPP-1 PDE10A,SIMA,object,THPP 1,recognition,Phosphodiesterase (PDE),Inhibitor,inhibit,novel,THPP-1,THPP1 Methanone, [2-(6-chloro-3-pyridinyl)-7,8-dihydro-4-(2-methoxyethoxy)pyrido[4,3-d]pyrimidin-6(5H)-yl]imidazo[1,5-a]pyridin-1-yl- 1257051-63-0