MONOBROMOBIMANE
- CAS No.
- 71418-44-5
- Chemical Name:
- MONOBROMOBIMANE
- Synonyms
- MMB;MBBR;Nsc 608544;BROMOBIMANE;THIOLYTE(R) MB;MONOBROMOBIMANE;Bromobimane >THIOLYTE(R) MB REAGENT;MBBr [MonobroMobiMane];Special fluorescent reagent
- CBNumber:
- CB0729365
- Molecular Formula:
- C10H11BrN2O2
- Molecular Weight:
- 271.11
- MDL Number:
- MFCD00036951
- MOL File:
- 71418-44-5.mol
| Melting point | 152-154 °C(lit.) |
|---|---|
| Boiling point | 327.8±44.0 °C(Predicted) |
| Density | 1.66±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: soluble |
| pka | -3.36±0.70(Predicted) |
| form | powder |
| color | Yellow |
| λmax | 398 nm |
| BRN | 4430959 |
| Stability | Light Sensitive |
| Biological Applications | Glutathione S-transferase substrates; detecting glutathione S-transferase,thiols,sulfite,homocysteine,mycothiol,sulfur compounds; thiol-reactive probes |
| CAS DataBase Reference | 71418-44-5 |
| FDA UNII | V23UK0CYXL |
MONOBROMOBIMANE price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 596105 | Bromobimane | 71418-44-5 | 25mg | $158 | 2024-03-01 | Buy |
| Sigma-Aldrich | 596105 | Bromobimane | 71418-44-5 | 100mg | $491 | 2024-03-01 | Buy |
| Sigma-Aldrich | 69898 | Bromobimane BioReagent, suitable for fluorescence, ≥95% (HPCE) | 71418-44-5 | 25MG | $151 | 2023-06-20 | Buy |
| Sigma-Aldrich | 69898 | Bromobimane BioReagent, suitable for fluorescence, ≥95% (HPCE) | 71418-44-5 | 100MG | $484 | 2023-06-20 | Buy |
| TCI Chemical | B4220 | Bromobimane >98.0%(HPLC) | 71418-44-5 | 20mg | $227 | 2024-03-01 | Buy |
MONOBROMOBIMANE Chemical Properties,Uses,Production
Description
Monobromobimane is a thiol-reactive fluorogenic probe. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The absorption and emission maxima for monobromobimane are 398 and 490 nm, respectively.
Chemical Properties
Yellow Powder
Uses
Monobromobimane readily reacts with low molecular weight thiols. Bimanes are useful for detecting the distribution of protein thiols in cells before and after chemical reduction of disulfides. Fluorescence: max. Abs. 398nm; e x 10-3: 5.0
Uses
double labeled product that can be fixed with aldehydes for cell-lineage tracing1, neuronal tracing2 and transplantation3.
Uses
Monobromobimane is a thiol-reactive fluorogenic probe. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The absorption and emission maxima for monobromobimane are 398 and 490 nm, respectively.
Uses
Monobromobimane is essentially nonfluorescent until conjugated to target molecule. It readily reacts with several low molecular weight thiols, including glutathione, mercaptopurine, peptides and plasma thiols, as well as with carboxylic acids.
Definition
ChEBI: A pyrazolopyrazole that consists of 1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione bearing three methyl substituents at positions 2, 5 and 6 as well as a bromomethyl substituent at the 3-position.
MONOBROMOBIMANE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12731 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Mascot I.E.Co .,Ltd. | +86-0519-85010339 +8613584504415 | info@mascotchem.com | China | 309 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |