ANTI-CHOLERA TOXIN
- CAS No.
- Chemical Name:
- ANTI-CHOLERA TOXIN
- Synonyms
- ANTI-CHOLERA TOXIN;ANTI-VIBRIO CHOLERA TOXIN;Anti-Cholera Toxin antibody produced in rabbit
- CBNumber:
- CB0739151
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00162231
- MOL File:
- Mol file
ANTI-CHOLERA TOXIN price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C3062 | Anti-Cholera Toxin antibody produced in rabbit whole antiserum | 1mL | $396 | 2024-03-01 | Buy | |
American Custom Chemicals Corporation | ATB0010809 | ANTI-VIBRIO CHOLERA TOXIN 95.00% | 5MG | $495.31 | 2021-12-16 | Buy |
ANTI-CHOLERA TOXIN Chemical Properties,Uses,Production
Uses
Anti-Cholera Toxin antibody produced in rabbit has been used in:
- western blotting
- quantitative ganglioside-dependent enzyme-linked immunoassay (ELISA)
- double immunodiffusion
General Description
Cholera toxin, the pathogenic agent of cholera, is made of two subunits, A (27 kDa) and B (12 kDa) assembled with the stoichiometry AB5. The B-subunit binds to specific receptors, the monosialogangliosides GM1, located in the membrane of intestinal epithelial cells. The A1 fragment of the A-subunit is translocated through the membrane of the host cell, where it catalyses the ADP-ribosylation of the Gsa regulatory component of the adenylate cyclase complex. The resulting increased level of cyclic AMP promotes a wide variety of actions, including the secretion of chloride ions in the case of intestinal epithelial cells.
Biochem/physiol Actions
Cholera toxin (CT), a multifunctional protein plays a role in the immune system. It possesses immunomodulatory, adjuvant properties and also acts as an anti-inflammatory agent. Its immunomodulatory properties can be utilized to treat several autoimmune disorders. CT can serve as one of the best model of a multifunctional protein.
ANTI-CHOLERA TOXIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-CHOLERA TOXIN Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |