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α-Amanitin

α-Amanitin structure

CAS No.: 11030-71-0

Chemical Name:: α-Amanitin

Synonyms: α-Amanitin

CBNumber:: CB0944238

Molecular Formula:: C39H53N9O14S

Molecular Weight:: 903.95502

MDL Number:

MOL File:: 11030-71-0.mol

Last updated:2022-12-21 16:56:50

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α-Amanitin Properties

Melting point	245 °C (decomp)
FDA UNII	6429KFN06D

SAFETY

Risk and Safety Statements

Toxicity	A drug derived from the highly poisonous fungus Amanita phalloides (death cap). Alpha-amanitin, a cyclic octapeptide, is toxic because of its affinity for RNA polymerase II in eukaryotic cells. Since this enzyme is responsible for mRNA synthesis in the cell, the compound is a potent and selective inhibitor of mRNA synthesis. It is effective at concentrations below 1 μg/mL, and its specific action has made it useful in experimental biology. It is often used with actinomycin D to block RNA synthesis.

Toxicity

A drug derived from the highly poisonous fungus Amanita phalloides (death cap). Alpha-amanitin, a cyclic octapeptide, is toxic because of its affinity for RNA polymerase II in eukaryotic cells. Since this enzyme is responsible for mRNA synthesis in the cell, the compound is a potent and selective inhibitor of mRNA synthesis. It is effective at concentrations below 1 μg/mL, and its specific action has made it useful in experimental biology. It is often used with actinomycin D to block RNA synthesis.

α-Amanitin Preparation Products And Raw materials

Raw materials

Preparation Products

α-Amanitin Suppliers

Global( 29)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58

Supplier	Advantage
Career Henan Chemica Co	58

α-Amanitin 11030-71-0 C39H54N10O13S