ChemicalBook >> CAS DataBase List >>4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]-

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]-

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- structure

CAS No.: 2640567-43-5

Chemical Name:: 4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]-

Synonyms: INE963;uncomplicated malaria,inhibit,INE 963,Parasite,INE963,antimalarial,Inhibitor,INE-963;4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]-

CBNumber:: CB110690988

Molecular Formula:: C19H26N6O2S

Molecular Weight:: 402.51

MDL Number:

MOL File:: 2640567-43-5.mol

Last updated:2023-09-04 15:51:00

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4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- Properties

Density	1.44±0.1 g/cm3(Predicted)
storage temp.	4°C, protect from light
pka	12.24±0.20(Predicted)

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- Chemical Properties,Uses,Production

Biological Activity

INE963 is a potent and fast-acting blood-stage antimalarial agent, with an EC50s of 3-6 nM. INE963 is potential for single-dose cures in uncomplicated malaria[1].

References

[1]. Taft BR, et, al. Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria. J Med Chem. 2022 Mar 10;65(5):3798-3813.

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- Suppliers

Global( 15)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4604	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3423	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4153	55
ShangHai Biochempartner Co.,Ltd	17754423994 17754423994	2853530910@QQ.com	China	8011	62
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9767	58
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	chaolaichem@foxmail.com	China	9038	58
Fujian boshi pharmaceutical technology co. LTD	18120708884	393612455@qq.com	China	255	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
ShangHai Biochempartner Co.,Ltd	62
Shanghai Chaolan Chemical Technology Center	58
Shanghai SuperLan Chemcial Technique Centre	58
Fujian boshi pharmaceutical technology co. LTD	58
DC Chemicals	58

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- Spectrum

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]-(2640567-43-5)¹HNMR

4-Piperidinol, 4-(aminomethyl)-1-[5-[2-methoxy-6-(1-methylethyl)-3-pyridinyl]imidazo[2,1-b]-1,3,4-thiadiazol-2-yl]- INE963 uncomplicated malaria,inhibit,INE 963,Parasite,INE963,antimalarial,Inhibitor,INE-963 2640567-43-5