L-Tyrosine, 3-hydroxy-, monosodium salt (9CI)
- CAS No.
- 63302-01-2
- Chemical Name:
- L-Tyrosine, 3-hydroxy-, monosodium salt (9CI)
- Synonyms
- Levodopa sodium;L-Tyrosine, 3-hydroxy-, monosodium salt (9CI)
- CBNumber:
- CB110719476
- Molecular Formula:
- C9H12NNaO4
- Molecular Weight:
- 221.19
- MDL Number:
- MOL File:
- 63302-01-2.mol
L-Tyrosine, 3-hydroxy-, monosodium salt (9CI) Chemical Properties,Uses,Production
Description
Levodopa is the naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE.
in vitro
SH-SY5Y cells were treated with CA (carnosic acid) for 18 h, and then co-treated with 400 μM L-dopa for the indicated time points. The results showed that pretreatment of CA attenuated the cell death and nuclear condensation induced by L-dopa. In conclusion, CA ameliorates the development of LID via regulating the D1R signaling and prevents L-dopa-induced apoptotic cell death through modulating the ERK1/2-c-Jun and inducing the parkin._x000D_ _x000D_ Reference: Front Pharmacol. 2021 Aug 9;12:703894. https://pubmed.ncbi.nlm.nih.gov/34434108/
in vivo
These results confirm previous findings that rotenone-induced motor and non-motor problems were alleviated by the Active diet (AD). Levodopa showed an additive beneficial effect on rotarod performance in rotenone-treated mice fed with the AD._x000D_ _x000D_ Reference: Front Aging Neurosci. 2018 Aug 3;10:237. https://pubmed.ncbi.nlm.nih.gov/30127735/
target
L-DOPA (Levodopa) sodium is an orally active metabolic precursor of neurotransmitters dopamine.
L-Tyrosine, 3-hydroxy-, monosodium salt (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
L-Tyrosine, 3-hydroxy-, monosodium salt (9CI) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
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TargetMol Chemicals Inc. | 58 |