SEX HORMONE BINDING GLOBULIN
- CAS No.
- Chemical Name:
- SEX HORMONE BINDING GLOBULIN
- Synonyms
- SHBG;TEBG;HSHBG;HTEBG;SHBG, HUMAN;SEX HORMONE BINDING GLOBULIN;SEX HORMONE BINDING GLOBULIN, HUMAN;TESTOSTERONE-ESTRADIOL BINDING GLOBULIN;Recombinant Human SHBG Protein, His Tag;TESTOSTERONE-ESTRADIOL BINDING GLOBULIN, HUMAN
- CBNumber:
- CB1125683
- Molecular Formula:
- Molecular Weight:
- 612.74
- MDL Number:
- MFCD00163748
- MOL File:
- Mol file
| storage temp. | −20°C |
|---|---|
| form | buffered aqueous glycerol solution |
| FDA UNII | YJ0ZSQ5NF5 |
SAFETY
Risk and Safety Statements
| Hazard Codes | B |
|---|---|
| WGK Germany | 1 |
SEX HORMONE BINDING GLOBULIN price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S1437 | Sex Hormone-Binding Globulin from human serum ≥95% (SDS-PAGE), buffered aqueous glycerol solution | 10μG | $699 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB1304899 | ANTI-SHBG (N-TERM) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μl | $461 | 2023-01-07 | Buy | |
| Usbiological | 358838 | SHBG | 48Tests | $588 | 2021-12-16 | Buy | |
| Usbiological | 358837 | SHBG | 48Tests | $588 | 2021-12-16 | Buy | |
| Usbiological | 156782 | Sex Hormone Binding Globulin | 10ug | $320 | 2021-12-16 | Buy |
SEX HORMONE BINDING GLOBULIN Chemical Properties,Uses,Production
Uses
Sex hormone binding globulin (SHBG) from human serum has been used as a spiked sample in radioimmunoassay. It may also be used to study the effects of hydroxylated estrogen metabolites (2-OH-E2 and 4-OH-E2) on the mRNA and protein expression of SHBG in MCF-7 human breast cancer cell line.
General Description
Sex hormone binding globulin (SHBG) is secreted by the liver. It is also expressed in the endometrium, ovary and testis. SHBG is composed of 402 amino acids and the gene encoding it is localized on human chromosome 17p12–p13.
Biochem/physiol Actions
Sex hormone binding globulin (SHBG) is a dimeric plasma glycoprotein with high affinity for the gonadal steroids, testosterone and estradiol. It regulates the availability of sex steroid hormones and limits their access to target cells. SHBG also inhibits estradiol-induced proliferation of breast cancer cells. Alterations in the expression of the protein have been linked to male infertility.
SEX HORMONE BINDING GLOBULIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 | honestchemical@foxmail.com | China | 247 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10055 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6960 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
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